Reactive Species from Two-Signal Activated Macrophages Interfere with Their Oxygen Consumption Measurements.

classically activated macrophages (M1) nitric oxide (NO●) oxygen consumption reactive oxygen/nitrogen species (ROS/RNS) respiration superoxide anion (O2●−)

Journal

Antioxidants (Basel, Switzerland)
ISSN: 2076-3921
Titre abrégé: Antioxidants (Basel)
Pays: Switzerland
ID NLM: 101668981

Informations de publication

Date de publication:
20 Jul 2021
Historique:
received: 10 06 2021
revised: 15 07 2021
accepted: 16 07 2021
entrez: 6 8 2021
pubmed: 7 8 2021
medline: 7 8 2021
Statut: epublish

Résumé

Metabolic modulation of macrophage activation has emerged as a promising strategy lately in immunotherapeutics. However, macrophages have a broad spectrum of functions and thus, understanding the exact metabolic changes that drive a particular immune response, is of major importance. In our previous work, we have reported a key role of nitric oxide (NO

Identifiants

pubmed: 34356382
pii: antiox10071149
doi: 10.3390/antiox10071149
pmc: PMC8301004
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Helse Sør-Øst RHF
ID : 2019059
Organisme : Helse Sør-Øst RHF
ID : 2017116

Références

Am J Physiol Regul Integr Comp Physiol. 2004 Nov;287(5):R1014-30
pubmed: 15475499
Int Rev Immunol. 2015 Jan;34(1):82-100
pubmed: 25340307
Biochem J. 2001 Jan 15;353(Pt 2):411-6
pubmed: 11139407
J Physiol. 2003 Oct 15;552(Pt 2):335-44
pubmed: 14561818
Cell Rep. 2016 Oct 11;17(3):684-696
pubmed: 27732846
Circ Res. 2009 May 22;104(10):1136-8
pubmed: 19461104
Amino Acids. 2003 Dec;25(3-4):207-18
pubmed: 14661084
J Biol Chem. 1997 Feb 21;272(8):4959-63
pubmed: 9030556
Front Immunol. 2018 Nov 02;9:2520
pubmed: 30450098
Front Immunol. 2014 Sep 02;5:420
pubmed: 25228902
Biochim Biophys Acta. 2008 Jul-Aug;1777(7-8):789-93
pubmed: 18455501
Biochemistry. 1992 May 5;31(17):4296-303
pubmed: 1567875
Free Radic Res Commun. 1993;18(4):195-9
pubmed: 8396550
Free Radic Biol Med. 1999 Feb;26(3-4):463-71
pubmed: 9895239
Circ Res. 2000 May 12;86(9):960-6
pubmed: 10807868
Arch Biochem Biophys. 1985 Mar;237(2):408-14
pubmed: 2983613
J Neurochem. 2003 Jan;84(1):112-8
pubmed: 12485407
Free Radic Biol Med. 2001 Mar 1;30(5):463-88
pubmed: 11182518
J Biol Chem. 2003 Sep 26;278(39):37223-30
pubmed: 12857734
Physiol Rev. 2014 Jul;94(3):909-50
pubmed: 24987008
Biochem Biophys Res Commun. 1995 Apr 17;209(2):739-43
pubmed: 7733945
Talanta. 2001 Jun 21;54(5):785-803
pubmed: 18968301
Arch Biochem Biophys. 1998 Dec 15;360(2):187-94
pubmed: 9851830
Biotechnol Annu Rev. 2005;11:127-52
pubmed: 16216776
J Vis Exp. 2015 Nov 28;(105):
pubmed: 26649578
Cell. 2017 May 4;169(4):570-586
pubmed: 28475890
Front Neuroenergetics. 2010 Feb 03;2:1
pubmed: 20162100
Biochem J. 2011 Apr 15;435(2):297-312
pubmed: 21726199
Biochem J. 2001 Aug 1;357(Pt 3):593-615
pubmed: 11463332
J Immunol. 2000 Jun 15;164(12):6166-73
pubmed: 10843666
J Neurochem. 2006 Jun;97(6):1676-89
pubmed: 16805776
Front Immunol. 2017 Oct 26;8:1383
pubmed: 29123526
Mitochondrion. 2019 May;46:380-392
pubmed: 30391711

Auteurs

Panagiotis F Christopoulos (PF)

Tumor Immunology Lab, Department of Pathology, Rikshospitalet, Oslo University Hospital and University of Oslo, 0424 Oslo, Norway.

Mantas Grigalavicius (M)

Department of Radiation Biology, Institute for Cancer Research, Oslo University Hospital, 0379 Oslo, Norway.

Alexandre Corthay (A)

Tumor Immunology Lab, Department of Pathology, Rikshospitalet, Oslo University Hospital and University of Oslo, 0424 Oslo, Norway.

Kristian Berg (K)

Department of Radiation Biology, Institute for Cancer Research, Oslo University Hospital, 0379 Oslo, Norway.

Theodossis A Theodossiou (TA)

Department of Radiation Biology, Institute for Cancer Research, Oslo University Hospital, 0379 Oslo, Norway.

Classifications MeSH