A Case of Tracheal Stenosis as an Isolated Form of Immunoproliferative Hyper-IgG4 Disease in a 17-Year-Old Girl.

IgG4 immunoproliferative disease children tracheal stenosis

Journal

Children (Basel, Switzerland)
ISSN: 2227-9067
Titre abrégé: Children (Basel)
Pays: Switzerland
ID NLM: 101648936

Informations de publication

Date de publication:
12 Jul 2021
Historique:
received: 29 05 2021
revised: 29 06 2021
accepted: 09 07 2021
entrez: 6 8 2021
pubmed: 7 8 2021
medline: 7 8 2021
Statut: epublish

Résumé

Immunoglobulin G4-related disease (IgG4-RD) is a lymphoproliferative disease which is described almost exclusively in adults. There are only a few pediatric patients who have been observed with this disorder. Here, we describe a rare case of IgG4-RD in a 17-year-old girl with a single manifestation-tracheal stenosis without previous intubation or other inciting event. She had mixed dyspnea and noisy and weakened breathing. Immunoproliferative hyper-IgG4 disease was diagnosed, based on elevated serum IgG4 and histological findings. Until now we have chosen to treat the girl only with corticosteroids with a good response so far. The general condition as well as the respiratory function are regularly monitored. The tracheal involvement of IgG4-RD is uncommon. Nonetheless, it is a manifestation that should be included in the differential diagnosis of tracheal stenosis.

Identifiants

pubmed: 34356568
pii: children8070589
doi: 10.3390/children8070589
pmc: PMC8307327
pii:
doi:

Types de publication

Case Reports

Langues

eng

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Auteurs

Natalia Gabrovska (N)

Department of Pulmonary Diseases, Multiprofile Hospital for Active Treatment of Pulmonary Diseases "St. Sofia", Medical University-Sofia, 1431 Sofia, Bulgaria.

Svetlana Velizarova (S)

Department of Pulmonary Diseases, Multiprofile Hospital for Active Treatment of Pulmonary Diseases "St. Sofia", Medical University-Sofia, 1431 Sofia, Bulgaria.

Albena Spasova (A)

Department of Pulmonary Diseases, Multiprofile Hospital for Active Treatment of Pulmonary Diseases "St. Sofia", Medical University-Sofia, 1431 Sofia, Bulgaria.

Dimitar Kostadinov (D)

Department of Pulmonary Diseases, Multiprofile Hospital for Active Treatment of Pulmonary Diseases "St. Sofia", Medical University-Sofia, 1431 Sofia, Bulgaria.

Nikolay Yanev (N)

Department of Pulmonary Diseases, Multiprofile Hospital for Active Treatment of Pulmonary Diseases "St. Sofia", Medical University-Sofia, 1431 Sofia, Bulgaria.

Hristo Shivachev (H)

Department of Pediatric Thoracic Surgery, Pediatric Surgery Clinic, University Multiprofile Hospital for Active Treatment and Emergency Medicine "N. I. Pirogov", 1606 Sofia, Bulgaria.

Edmond Rangelov (E)

Department of Pediatric Thoracic Surgery, Pediatric Surgery Clinic, University Multiprofile Hospital for Active Treatment and Emergency Medicine "N. I. Pirogov", 1606 Sofia, Bulgaria.

Yanko Pahnev (Y)

Department of Pediatric Thoracic Surgery, Pediatric Surgery Clinic, University Multiprofile Hospital for Active Treatment and Emergency Medicine "N. I. Pirogov", 1606 Sofia, Bulgaria.

Zdravka Antonova (Z)

Department of Pediatric Thoracic Surgery, Pediatric Surgery Clinic, University Multiprofile Hospital for Active Treatment and Emergency Medicine "N. I. Pirogov", 1606 Sofia, Bulgaria.

Nikola Kartulev (N)

Department of Pediatric Thoracic Surgery, Pediatric Surgery Clinic, University Multiprofile Hospital for Active Treatment and Emergency Medicine "N. I. Pirogov", 1606 Sofia, Bulgaria.

Ivan Terziev (I)

Department of Pathology, University Hospital ''Tsaritsa Uoanna-ISUL'', 1527 Sofia, Bulgaria.

Kaloyan Gabrovski (K)

Department of Neurosurgery, University Hospital "St. Ivan Rilski", Medical University-Sofia, 1431 Sofia, Bulgaria.

Classifications MeSH