Microbiota Gut-Brain Axis in Ischemic Stroke: A Narrative Review with a Focus about the Relationship with Inflammatory Bowel Disease.

brain gut inflammatory bowel disease microbiota stroke

Journal

Life (Basel, Switzerland)
ISSN: 2075-1729
Titre abrégé: Life (Basel)
Pays: Switzerland
ID NLM: 101580444

Informations de publication

Date de publication:
19 Jul 2021
Historique:
received: 28 05 2021
revised: 04 07 2021
accepted: 13 07 2021
entrez: 6 8 2021
pubmed: 7 8 2021
medline: 7 8 2021
Statut: epublish

Résumé

The gut microbiota is emerging as an important player in neurodevelopment and aging as well as in brain diseases including stroke, Alzheimer's disease, and Parkinson's disease. The complex interplay between gut microbiota and the brain, and vice versa, has recently become not only the focus of neuroscience, but also the starting point for research regarding many diseases such as inflammatory bowel diseases (IBD). The bi-directional interaction between gut microbiota and the brain is not completely understood. The aim of this review is to sum up the evidencesconcerningthe role of the gut-brain microbiota axis in ischemic stroke and to highlight the more recent evidences about the potential role of the gut-brain microbiota axis in the interaction between inflammatory bowel disease and ischemic stroke.

Identifiants

pubmed: 34357086
pii: life11070715
doi: 10.3390/life11070715
pmc: PMC8305026
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Références

Nat Med. 2016 Nov;22(11):1277-1284
pubmed: 27694934
J Cereb Blood Flow Metab. 2020 Jul;40(7):1368-1380
pubmed: 32312168
Eur J Intern Med. 2014 Jul;25(6):561-5
pubmed: 24906568
Nat Med. 2016 May;22(5):516-23
pubmed: 27019327
Diabetes Res Clin Pract. 2021 Feb;172:108645
pubmed: 33359751
Brain Res. 2016 Jul 1;1642:180-188
pubmed: 27037183
Neurosci Lett. 2017 Sep 29;658:165-170
pubmed: 28859865
Nat Commun. 2018 Aug 17;9(1):3294
pubmed: 30120222
Gerodontology. 2017 Sep;34(3):343-356
pubmed: 28543778
Clin Ther. 2015 May 1;37(5):954-67
pubmed: 25846319
Am J Physiol Renal Physiol. 2013 Aug 15;305(4):F439-44
pubmed: 23761671
Stroke. 2019 Aug;50(8):2270-2277
pubmed: 31272315
Lancet Neurol. 2014 Aug;13(8):823-33
pubmed: 25030514
Anat Rec (Hoboken). 2012 Feb;295(2):307-12
pubmed: 22190447
Nat Commun. 2014 Apr 29;5:3611
pubmed: 24781306
Life Sci. 2021 Feb 1;266:118865
pubmed: 33301807
J Clin Med. 2018 Jan 03;7(1):
pubmed: 29301380
J Nutr Biochem. 2018 Jun;56:1-15
pubmed: 29427903
Hypertension. 2015 Jun;65(6):1331-40
pubmed: 25870193
PeerJ. 2019 Jun 12;7:e6928
pubmed: 31223522
Front Aging Neurosci. 2021 Feb 12;13:636545
pubmed: 33643026
PLoS One. 2017 Feb 6;12(2):e0171521
pubmed: 28166278
Medicine (Baltimore). 2018 Oct;97(41):e12805
pubmed: 30313111
J Cereb Blood Flow Metab. 2018 Aug;38(8):1293-1298
pubmed: 29846130
Zhonghua Liu Xing Bing Xue Za Zhi. 2008 Mar;29(3):294-6
pubmed: 18788533
Am J Physiol Gastrointest Liver Physiol. 2016 Jun 1;310(11):G989-98
pubmed: 27056723
Cell Metab. 2017 Oct 3;26(4):611-619.e6
pubmed: 28978426
Brain Circ. 2018 Oct-Dec;4(4):165-173
pubmed: 30693343
Transl Neurosci. 2020 Jun 08;11(1):124-133
pubmed: 33312718
Cell. 2018 Nov 1;175(4):947-961.e17
pubmed: 30401435
World J Gastroenterol. 2003 Dec;9(12):2776-81
pubmed: 14669332
J Am Heart Assoc. 2016 Aug 30;5(9):
pubmed: 27577581
Neurosci Lett. 2016 Feb 2;613:30-5
pubmed: 26733300
World J Clin Cases. 2020 Mar 26;8(6):1013-1025
pubmed: 32258072
Am J Gastroenterol. 2005 Nov;100(11):2560-8
pubmed: 16279914
Circ Res. 2015 Jan 30;116(3):448-55
pubmed: 25599331
Prog Neuropsychopharmacol Biol Psychiatry. 2021 Mar 2;106:110112
pubmed: 32949638
Atherosclerosis. 2016 Apr;247:64-9
pubmed: 26868510
Nat Rev Endocrinol. 2019 Dec;15(12):701-712
pubmed: 31616073
Nat Neurosci. 2015 Jul;18(7):965-77
pubmed: 26030851
Mucosal Immunol. 2018 Mar;11(2):369-379
pubmed: 28612842
Front Neurol. 2020 Jun 25;11:598
pubmed: 32670191
Nat Rev Immunol. 2020 Apr;20(4):217-228
pubmed: 31848462
Neurotherapeutics. 2016 Oct;13(4):762-774
pubmed: 27714645
Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16767-72
pubmed: 18931303
Transl Stroke Res. 2021 Aug;12(4):581-592
pubmed: 33052545
Prog Neuropsychopharmacol Biol Psychiatry. 2021 Mar 2;106:110091
pubmed: 32891667
J Microbiol Biotechnol. 2018 Jan 28;28(1):175-179
pubmed: 29081213
Sci Rep. 2019 Apr 23;9(1):6432
pubmed: 31015533
Ann Neurol. 2018 Jul;84(1):23-36
pubmed: 29733457
Porto Biomed J. 2021 Jan 18;6(1):e106
pubmed: 33490701
J Am Heart Assoc. 2015 Nov 23;4(11):
pubmed: 26597155
BMC Microbiol. 2019 Aug 19;19(1):191
pubmed: 31426765
Support Care Cancer. 2021 Feb;29(2):605-617
pubmed: 32918608
Cardiovasc Res. 2007 Jan 1;73(1):6-7
pubmed: 17156767
Crit Care. 2016 Dec 7;20(1):391
pubmed: 27923376
Nat Rev Gastroenterol Hepatol. 2017 Oct;14(10):573-584
pubmed: 28743984
Front Neurol. 2019 Apr 24;10:397
pubmed: 31068891
Int J Mol Sci. 2017 Aug 17;18(8):
pubmed: 28817088
Int J Stroke. 2018 Dec;13(9):913-920
pubmed: 30175940
J Thromb Thrombolysis. 2015 May;39(4):489-98
pubmed: 25115840
BMC Nephrol. 2018 Oct 22;19(1):283
pubmed: 30348107
Stroke. 2005 Dec;36(12):2756-63
pubmed: 16269630
World J Gastroenterol. 2015 Sep 7;21(33):9688-92
pubmed: 26361415
Brain Behav Immun. 2016 Oct;57:10-20
pubmed: 27060191
Eur J Gastroenterol Hepatol. 2016 Jan;28(1):1-7
pubmed: 26513610
Nat Rev Gastroenterol Hepatol. 2009 May;6(5):306-14
pubmed: 19404271
JPEN J Parenter Enteral Nutr. 2021 Mar;45(3):518-529
pubmed: 32473086
J Neurosci. 2016 Jul 13;36(28):7428-40
pubmed: 27413153
Bull World Health Organ. 2016 Sep 1;94(9):634-634A
pubmed: 27708464
Aging (Albany NY). 2016 May;8(5):1049-63
pubmed: 27115295
J Lipid Res. 2006 Jun;47(6):1227-37
pubmed: 16522925
Sci Rep. 2018 Jan 12;8(1):568
pubmed: 29330443
Neuroimmunomodulation. 2009;16(3):213-8
pubmed: 19246945
PLoS One. 2021 Jan 13;16(1):e0245038
pubmed: 33439913
Nutrients. 2021 Jan 03;13(1):
pubmed: 33401598

Auteurs

Emanuele Sinagra (E)

Endoscopy Unit, Fondazione Istituto San Raffaele-G. Giglio, Contrada Pietra Pollastra Pisciotto, 90015 Cefalù, Italy.
Euro-Mediterranean Institute of Science and Technology (IEMEST), 90100 Palermo, Italy.

Gaia Pellegatta (G)

Digestive Endoscopy Unit, Division of Gastroenterology, Humanitas Research Hospital, 20089 Rozzano, Italy.

Valentina Guarnotta (V)

Endocrinology Section, PROMISE Department, AOUP Paolo Giaccone, 90127 Palermo, Italy.

Marcello Maida (M)

Gastroenterology and Endoscopy Unit, S. Elia-Raimondi Hospital, 93100 Caltanissetta, Italy.

Francesca Rossi (F)

Endoscopy Unit, Fondazione Istituto San Raffaele-G. Giglio, Contrada Pietra Pollastra Pisciotto, 90015 Cefalù, Italy.

Giuseppe Conoscenti (G)

Endoscopy Unit, Fondazione Istituto San Raffaele-G. Giglio, Contrada Pietra Pollastra Pisciotto, 90015 Cefalù, Italy.

Socrate Pallio (S)

Endoscopy Unit, Department of clinical and experimental medicine, University of Messina, AOUP Policlinico G. Martino, 98125 Messina, Italy.

Rita Alloro (R)

Endoscopy Unit, Fondazione Istituto San Raffaele-G. Giglio, Contrada Pietra Pollastra Pisciotto, 90015 Cefalù, Italy.
Emergency Unit, Fondazione Istituto G. Giglio, Contrada Pietra Pollastra Pisciotto, 90015 Cefalù, Italy.

Dario Raimondo (D)

Endoscopy Unit, Fondazione Istituto San Raffaele-G. Giglio, Contrada Pietra Pollastra Pisciotto, 90015 Cefalù, Italy.

Fabio Pace (F)

Unit of Gastroenterology, Bolognini Hospital, 24100 Bergamo, Italy.

Andrea Anderloni (A)

Digestive Endoscopy Unit, Division of Gastroenterology, Humanitas Research Hospital, 20089 Rozzano, Italy.

Classifications MeSH