Multifaceted interconnections between macrophage migration inhibitory factor and psychiatric disorders.
Alzheimer's disease
Depressive disorder
Inflammation
Psychiatric disorders
Schizophrenia
Journal
Progress in neuro-psychopharmacology & biological psychiatry
ISSN: 1878-4216
Titre abrégé: Prog Neuropsychopharmacol Biol Psychiatry
Pays: England
ID NLM: 8211617
Informations de publication
Date de publication:
10 01 2022
10 01 2022
Historique:
received:
04
01
2021
revised:
30
07
2021
accepted:
31
07
2021
pubmed:
7
8
2021
medline:
15
2
2022
entrez:
6
8
2021
Statut:
ppublish
Résumé
Inflammation is involved in the pathogenesis of psychiatric disorders. Many previous studies have defined the important roles of inflammatory factors in the pathogenesis, diagnosis, and treatment outcomes of psychiatric disorders. Macrophage migration inhibitory factor (MIF), a pro-inflammatory factor, has been gradually recognized to be involved in the development of neurological diseases in recent years. Our current review focuses on discussing the potential beneficial and detrimental roles of MIF in psychiatric disorders. We will provide new mechanistic insights for the development of potential diagnostic and therapeutic biomarkers based on MIF for psychiatric diseases.
Identifiants
pubmed: 34358623
pii: S0278-5846(21)00181-0
doi: 10.1016/j.pnpbp.2021.110422
pii:
doi:
Substances chimiques
Biomarkers
0
Macrophage Migration-Inhibitory Factors
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
110422Informations de copyright
Copyright © 2021 Elsevier Inc. All rights reserved.