Sudden Cardiac Death Caused by a Fatal Association of Hypertrophic Cardiomyopathy (

LDLR MYH7 SARS-CoV-2 familial hypercholesterolemia fatal arrhythmia hypertrophic cardiomyopathy lineage B.1.1.7

Journal

Diagnostics (Basel, Switzerland)
ISSN: 2075-4418
Titre abrégé: Diagnostics (Basel)
Pays: Switzerland
ID NLM: 101658402

Informations de publication

Date de publication:
07 Jul 2021
Historique:
received: 05 06 2021
revised: 02 07 2021
accepted: 05 07 2021
entrez: 7 8 2021
pubmed: 8 8 2021
medline: 8 8 2021
Statut: epublish

Résumé

Hypertrophic cardiomyopathy (HCM) and heterozygous familial hypercholesterolemia (HeFH), two of the most common genetic cardiovascular disorders, can lead to sudden cardiac death. These conditions could be complicated by concomitant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection as in the case herein described. A young amateur soccer player died in late October 2020 after a fatal arrhythmia and the autopsy revealed the presence of HCM with diffuse non-obstructive coronary disease. The molecular autopsy revealed a compound condition with a first mutation in the

Identifiants

pubmed: 34359312
pii: diagnostics11071229
doi: 10.3390/diagnostics11071229
pmc: PMC8307649
pii:
doi:

Types de publication

Case Reports

Langues

eng

Subventions

Organisme : EMA
ID : F16C16000010005

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Auteurs

Nicola Marziliano (N)

Department of Medicine and Health Sciences "V. Tiberio", University of Molise, 86100 Campobasso, Italy.
Clinical Pathology Laboratory, ASST Rhodense, Rho, 20017 Milan, Italy.

Alessandro Medoro (A)

Department of Medicine and Health Sciences "V. Tiberio", University of Molise, 86100 Campobasso, Italy.

Donatella Mignogna (D)

Department of Medicine and Health Sciences "V. Tiberio", University of Molise, 86100 Campobasso, Italy.

Giovanni Saccon (G)

Department of Medicine and Health Sciences "V. Tiberio", University of Molise, 86100 Campobasso, Italy.

Stefano Folzani (S)

Poliambulatorio Città di Collecchio, Collecchio, 43044 Parma, Italy.

Claudio Reverberi (C)

Poliambulatorio Città di Collecchio, Collecchio, 43044 Parma, Italy.

Claudio Russo (C)

Department of Medicine and Health Sciences "V. Tiberio", University of Molise, 86100 Campobasso, Italy.

Mariano Intrieri (M)

Department of Medicine and Health Sciences "V. Tiberio", University of Molise, 86100 Campobasso, Italy.

Classifications MeSH