The Emerging Role of Circulating Tumor DNA in the Management of Breast Cancer.
breast cancer
chemotherapy
circulating tumor DNA
liquid biopsy
recurrence
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
29 Jul 2021
29 Jul 2021
Historique:
received:
08
07
2021
revised:
24
07
2021
accepted:
27
07
2021
entrez:
7
8
2021
pubmed:
8
8
2021
medline:
8
8
2021
Statut:
epublish
Résumé
With the incidence of breast cancer steadily rising, it is important to explore novel technologies that can allow for earlier detection of disease as well more a personalized and effective treatment approach. The concept of "liquid biopsies" and the data they provide have been increasingly studied in the recent decades. More specifically, circulating tumor DNA (ctDNA) has emerged as a potential biomarker for various cancers, including breast cancer. While methods such as mammography and tissue biopsies are the current standards for the detection and surveillance of breast cancer, ctDNA analysis has shown some promise. This review discusses the versatility of ctDNA by exploring its multiple emerging uses for the management of breast cancer. Its efficacy is also compared to current biomarkers and technologies.
Identifiants
pubmed: 34359713
pii: cancers13153813
doi: 10.3390/cancers13153813
pmc: PMC8345044
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
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