Reduced Endothelin-2 and Hypoxic Signaling Pathways in Granulosa-Lutein Cells of PCOS Women.

Adult Cells, Cultured Endothelin-2 / genetics Female Granulosa Cells / metabolism Humans Hypoxia-Inducible Factor 1, alpha Subunit / genetics Luteal Cells / metabolism MicroRNAs / genetics Polycystic Ovary Syndrome / metabolism Signal Transduction Vascular Endothelial Growth Factor A / genetics
HIF-1α VEGFA corpus luteum miR-210 ovulation

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
30 Jul 2021
Historique:
received: 21 06 2021
revised: 25 07 2021
accepted: 26 07 2021
entrez: 7 8 2021
pubmed: 8 8 2021
medline: 11 9 2021
Statut: epublish

Résumé

Granulosa-lutein cells (GLCs) from PCOS women display reduced

Identifiants

DOI: 10.3390/ijms22158216 PMID: 34360981 PMC: PMC8347025
pubmed: 34360981
pii: ijms22158216
doi: 10.3390/ijms22158216
pmc: PMC8347025
pii:
doi:

Substances chimiques

Endothelin-2 0
HIF1A protein, human 0
Hypoxia-Inducible Factor 1, alpha Subunit 0
MIRN210 microRNA, human 0
MicroRNAs 0
VEGFA protein, human 0
Vascular Endothelial Growth Factor A 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : the Robert H. Smith Faculty of Agriculture, Food and Environment Research Fund for International Cooperation scholarship
ID : N/A
Organisme : e German-Israeli Foundation for Scientific Research 379 and Development (GIF)
ID : I-1417

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Auteurs

Magdalena Szymanska (M)

Department of Animal Sciences, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot 7610001, Israel.
Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences, Tuwima 10, 10-748 Olsztyn, Poland.
ORCID: 0000-0002-7159-2256

Ketan Shrestha (K)

Department of Animal Sciences, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot 7610001, Israel.
UK Medical Center, Department of Obstetrics and Gynecology, University of Kentucky, Lexington, KY 40536, USA.

Eliezer Girsh (E)

Fertility and IVF Unit, Barzilai University Medical Center, Ashkelon 7830604, Israel.

Avi Harlev (A)

Fertility and IVF Unit, Barzilai University Medical Center, Ashkelon 7830604, Israel.
Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel.

Iris Eisenberg (I)

The Magda and Richard Hoffman Center for Human Placenta Research, Department of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, Jerusalem 91240, Israel.

Tal Imbar (T)

The Magda and Richard Hoffman Center for Human Placenta Research, Department of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, Jerusalem 91240, Israel.
Hadassah Ein Kerem Medical Center, Fertility Preservation Unit, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 9112102, Israel.
ORCID: 0000-0002-8583-1596

Rina Meidan (R)

Department of Animal Sciences, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot 7610001, Israel.
ORCID: 0000-0002-6727-6787

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Reduced Endothelin-2 and Hypoxic Signaling...
questionsmedicales.fr › Cellules › Cellules cultivées › Reduced Endothelin-2 and Hypoxic Signaling...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Endothélines › Endothéline-2 › Reduced Endothelin-2 and Hypoxic Signaling...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules de la granulosa › Reduced Endothelin-2 and Hypoxic Signaling...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Reduced Endothelin-2 and Hypoxic Signaling...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Facteurs de transcription à motif basique hélice-boucle-hélice › Facteur-1 induit par l'hypoxie › Sous-unité alpha du facteur-1 induit par l'hypoxie › Reduced Endothelin-2 and Hypoxic Signaling...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules lutéales › Reduced Endothelin-2 and Hypoxic Signaling...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › ARN non traduit › Petit ARN non traduit › microARN › Reduced Endothelin-2 and Hypoxic Signaling...
questionsmedicales.fr › Maladies endocriniennes › Troubles gonadiques › Maladies ovariennes › Kystes de l'ovaire › Syndrome des ovaires polykystiques › Reduced Endothelin-2 and Hypoxic Signaling...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › Reduced Endothelin-2 and Hypoxic Signaling...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Protéines angiogéniques › Facteurs de croissance endothéliale vasculaire › Facteur de croissance endothéliale vasculaire de type A › Reduced Endothelin-2 and Hypoxic Signaling...