Hyperuricemia Is an Early and Relatively Common Feature in Children with

FEUA HNF1B PTH hyperuricemia renal function uric acid

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
24 Jul 2021
Historique:
received: 30 05 2021
revised: 19 07 2021
accepted: 21 07 2021
entrez: 7 8 2021
pubmed: 8 8 2021
medline: 8 8 2021
Statut: epublish

Résumé

Hyperuricemia is recognized as an important feature of nephropathy, associated with a mutation in the hepatocyte nuclear factor-1B We performed a retrospective analysis of clinical characteristics of pediatric patients tested for 108 children were included in the study, comprising 43 mut+ patients and 65 mut- subjects. Mean sUA was higher and hyperuricemia more prevalent (42.5% vs. 15.4%) in Hyperuricemia is an early and common feature of

Sections du résumé

BACKGROUND BACKGROUND
Hyperuricemia is recognized as an important feature of nephropathy, associated with a mutation in the hepatocyte nuclear factor-1B
METHODS METHODS
We performed a retrospective analysis of clinical characteristics of pediatric patients tested for
RESULTS RESULTS
108 children were included in the study, comprising 43 mut+ patients and 65 mut- subjects. Mean sUA was higher and hyperuricemia more prevalent (42.5% vs. 15.4%) in
CONCLUSIONS CONCLUSIONS
Hyperuricemia is an early and common feature of

Identifiants

pubmed: 34362049
pii: jcm10153265
doi: 10.3390/jcm10153265
pmc: PMC8346958
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Marcin Kołbuc (M)

Department of Pediatrics, University of Zielona Góra, 65-417 Zielona Góra, Poland.

Beata Bieniaś (B)

Department of Pediatric Nephrology, Medical University of Lublin, 20-059 Lublin, Poland.

Sandra Habbig (S)

Department of Pediatrics, University Hospital of Cologne, 50937 Cologne, Germany.

Mateusz F Kołek (MF)

Department of Animal Physiology, Faculty of Biology, University of Warsaw, 00-927 Warsaw, Poland.

Maria Szczepańska (M)

Department of Pediatrics, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, 41-808 Zabrze, Poland.

Katarzyna Kiliś-Pstrusińska (K)

Department of Paediatric Nephrology, Wrocław Medical University, 50-367 Wrocław, Poland.

Anna Wasilewska (A)

Department of Pediatric Nephrology, University Hospital, 15-089 Białystok, Poland.

Piotr Adamczyk (P)

Department of Pediatrics, Faculty of Medical Sciences in Katowice, Medical University of Silesia in Katowice, 40-752 Katowice, Poland.

Rafał Motyka (R)

Department of Pediatrics, University of Zielona Góra, 65-417 Zielona Góra, Poland.

Marcin Tkaczyk (M)

Department of Pediatrics, Immunology and Nephrology, Polish Mother's Memorial Hospital Research Institute, 93-338 Łódź, Poland.

Przemysław Sikora (P)

Department of Pediatric Nephrology, Medical University of Lublin, 20-059 Lublin, Poland.

Bodo B Beck (BB)

Institute of Human Genetics and Center for Molecular Medicine Cologne, University of Cologne, Faculty of Medicine and University Hospital Cologne, 50937 Cologne, Germany.

Marcin Zaniew (M)

Department of Pediatrics, University of Zielona Góra, 65-417 Zielona Góra, Poland.

Classifications MeSH