Lesion Geometry as Assessed by Optical Coherence Tomography Is Related to Myocardial Ischemia as Determined by Cardiac Magnetic Resonance Imaging.

cardiac magnetic resonance imaging coronary artery disease optical coherence tomography stenosis geometry

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
28 Jul 2021
Historique:
received: 05 06 2021
revised: 11 07 2021
accepted: 16 07 2021
entrez: 7 8 2021
pubmed: 8 8 2021
medline: 8 8 2021
Statut: epublish

Résumé

Although the relationship between the geometry of coronary stenosis and the presence of myocardial ischemia is well known, the association between stenosis geometry and severity and/or extent of ischemia is still unexplored. Thus, we investigated this relationship using optical coherence tomography (OCT) to assess stenosis parameters and cardiac magnetic resonance imaging (CMR) to determine both extent and severity of ischemia. We analyzed 55 lesions from 51 patients with stable angina. Pre-interventionally, all patients underwent OCT-analysis of stenosis morphology as well as CMR to determine both the extent and severity of myocardial ischemia. Percent area stenosis (%AS) was significantly associated with ischemic burden (r = 0.416, Our data highlight the key role of the geometry of coronary lesions in determining myocardial ischemia.

Identifiants

pubmed: 34362126
pii: jcm10153342
doi: 10.3390/jcm10153342
pmc: PMC8348708
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Rosalia Dettori (R)

Department of Internal Medicine I, University Hospital of the RWTH Aachen, 52070 Aachen, Germany.

Andrea Milzi (A)

Department of Internal Medicine I, University Hospital of the RWTH Aachen, 52070 Aachen, Germany.

Michael Frick (M)

Department of Internal Medicine I, University Hospital of the RWTH Aachen, 52070 Aachen, Germany.

Kathrin Burgmaier (K)

Department of Pediatrics, University Hospital of Cologne, 50937 Cologne, Germany.

Mohammad Almalla (M)

Department of Internal Medicine I, University Hospital of the RWTH Aachen, 52070 Aachen, Germany.

Richard Karl Lubberich (RK)

Department of Internal Medicine I, University Hospital of the RWTH Aachen, 52070 Aachen, Germany.

Nikolaus Marx (N)

Department of Internal Medicine I, University Hospital of the RWTH Aachen, 52070 Aachen, Germany.

Sebastian Reith (S)

Department of Internal Medicine I, University Hospital of the RWTH Aachen, 52070 Aachen, Germany.

Mathias Burgmaier (M)

Department of Internal Medicine I, University Hospital of the RWTH Aachen, 52070 Aachen, Germany.

Classifications MeSH