Sars-Cov-2 virus and vaccination; biological and statistical framework.


Journal

Expert review of vaccines
ISSN: 1744-8395
Titre abrégé: Expert Rev Vaccines
Pays: England
ID NLM: 101155475

Informations de publication

Date de publication:
09 2021
Historique:
pubmed: 10 8 2021
medline: 24 9 2021
entrez: 9 8 2021
Statut: ppublish

Résumé

The Development of the SARS-CoV-2 virus vaccine and its update on an ongoing pandemic is the first subject of the world health agenda. First, we will scrutinize the biological features of the measles virus (MV), variola virus (smallpox virus), influenza virus, and their vaccines to compare them with the SARS-CoV-2 virus and vaccine. Next, we will discuss the statistical details of measuring the effectiveness of an improved vaccine. Amidst the pandemic, we ought to acknowledge our prior experiences with respiratory viruses and vaccines. In the planning stage of observational Phase-III vaccine effectiveness studies, the sample size, sampling method, statistical model, and selection of variables are crucial in obtaining high-quality and valid results.

Identifiants

pubmed: 34365880
doi: 10.1080/14760584.2021.1965884
pmc: PMC8425431
doi:

Substances chimiques

COVID-19 Vaccines 0
Influenza Vaccines 0
Measles-Mumps-Rubella Vaccine 0
Smallpox Vaccine 0
Vaccines, Attenuated 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1059-1063

Auteurs

Ferhat Arslan (F)

Department of Infectious Diseases and Clinical Microbiology, Istanbul Medeniyet University, Istanbul, Turkey.

Handan Ankaralı (H)

Department of Biostatistics, Istanbul Medeniyet University, Istanbul, Turkey.

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Classifications MeSH