Restricted Use of Echocardiography in Suspected Endocarditis during COVID-19 Lockdown: A Multidisciplinary Team Approach.


Journal

Cardiology research and practice
ISSN: 2090-8016
Titre abrégé: Cardiol Res Pract
Pays: United States
ID NLM: 101516542

Informations de publication

Date de publication:
2021
Historique:
received: 15 02 2021
revised: 24 06 2021
accepted: 24 07 2021
entrez: 9 8 2021
pubmed: 10 8 2021
medline: 10 8 2021
Statut: epublish

Résumé

Infective endocarditis (IE) is challenging to manage in the COVID-19 lockdown period, in part given its reliance on echocardiography for diagnosis and management and the associated virus transmission risks to patients and healthcare workers. This study assesses utilisation of the endocarditis team (ET) in limiting routine echocardiography, especially transoesophageal echocardiography (TOE), in patients with suspected IE, and explores the effect on clinical outcomes. All patients discussed at the ET meeting at Imperial College Healthcare NHS Trust during the first lockdown in the UK (23 March to 8 July 2020) were prospectively included and analysed in this observational study. In total, 38 patients were referred for ET review (71% male, median age 54 [interquartile range 48, 65.5] years). At the time of ET discussion, 21% had no echo imaging, 16% had point-of-care ultrasound only, and 63% had formal TTE. In total, only 16% underwent TOE. The ability of echocardiography, in those where it was performed, to affect IE diagnosis according to the Modified Duke Criteria was significant ( Limiting echocardiography in patients with a low pretest probability (not probable or definite IE according to the Modified Duke Criteria) did not affect the diagnostic ability of the Modified Duke Criteria to rule out IE in this small study. Moreover, restricting nonessential echocardiography, and importantly TOE, in patients with suspected IE through use of the ET did not impact all-cause mortality.

Sections du résumé

BACKGROUND BACKGROUND
Infective endocarditis (IE) is challenging to manage in the COVID-19 lockdown period, in part given its reliance on echocardiography for diagnosis and management and the associated virus transmission risks to patients and healthcare workers. This study assesses utilisation of the endocarditis team (ET) in limiting routine echocardiography, especially transoesophageal echocardiography (TOE), in patients with suspected IE, and explores the effect on clinical outcomes.
METHODS METHODS
All patients discussed at the ET meeting at Imperial College Healthcare NHS Trust during the first lockdown in the UK (23 March to 8 July 2020) were prospectively included and analysed in this observational study.
RESULTS RESULTS
In total, 38 patients were referred for ET review (71% male, median age 54 [interquartile range 48, 65.5] years). At the time of ET discussion, 21% had no echo imaging, 16% had point-of-care ultrasound only, and 63% had formal TTE. In total, only 16% underwent TOE. The ability of echocardiography, in those where it was performed, to affect IE diagnosis according to the Modified Duke Criteria was significant (
CONCLUSION CONCLUSIONS
Limiting echocardiography in patients with a low pretest probability (not probable or definite IE according to the Modified Duke Criteria) did not affect the diagnostic ability of the Modified Duke Criteria to rule out IE in this small study. Moreover, restricting nonessential echocardiography, and importantly TOE, in patients with suspected IE through use of the ET did not impact all-cause mortality.

Identifiants

pubmed: 34367691
doi: 10.1155/2021/5565200
pmc: PMC8342166
doi:

Types de publication

Journal Article

Langues

eng

Pagination

5565200

Subventions

Organisme : Wellcome Trust
Pays : United Kingdom

Informations de copyright

Copyright © 2021 Adam Hartley et al.

Déclaration de conflit d'intérêts

The authors declare no conflicts of interest.

Références

Echocardiography. 2020 Aug;37(8):1278-1286
pubmed: 32654210
Cardiovasc Diagn Ther. 2017 Feb;7(1):27-35
pubmed: 28164010
Clin Infect Dis. 2000 Apr;30(4):633-8
pubmed: 10770721
Clujul Med. 2015;88(3):321-6
pubmed: 26609264
Eur Heart J. 2015 Nov 21;36(44):3075-3128
pubmed: 26320109
BMJ Open. 2019 Apr 20;9(4):e026811
pubmed: 31005935
Can J Anaesth. 2020 Aug;67(8):1101-1103
pubmed: 32314264
Eur Heart J Cardiovasc Imaging. 2020 Jun 1;21(6):592-598
pubmed: 32242891
PLoS One. 2019 Oct 25;14(10):e0223857
pubmed: 31652280
Arch Intern Med. 2009 Jul 27;169(14):1290-8
pubmed: 19636030
Arch Intern Med. 2009 Mar 9;169(5):463-73
pubmed: 19273776
Eur Heart J. 2019 Oct 14;40(39):3222-3232
pubmed: 31504413

Auteurs

Adam Hartley (A)

National Heart and Lung Institute, Imperial College London, London, UK.
Imperial College Healthcare NHS Trust, London, UK.

Ahmed El-Sayed (A)

Imperial College Healthcare NHS Trust, London, UK.

Aula Abbara (A)

Imperial College Healthcare NHS Trust, London, UK.

Jamie Henderson (J)

Imperial College Healthcare NHS Trust, London, UK.

Anan Ghazy (A)

Imperial College Healthcare NHS Trust, London, UK.

Frances Davies (F)

Imperial College Healthcare NHS Trust, London, UK.
NIHR Health Protection Research Unit in HCAI and AMR, Imperial College London, London, UK.

James R Price (JR)

Imperial College Healthcare NHS Trust, London, UK.
NIHR Health Protection Research Unit in HCAI and AMR, Imperial College London, London, UK.

Prakash P Punjabi (PP)

National Heart and Lung Institute, Imperial College London, London, UK.
Imperial College Healthcare NHS Trust, London, UK.

Jon Anderson (J)

Imperial College Healthcare NHS Trust, London, UK.

Roberto Casula (R)

Imperial College Healthcare NHS Trust, London, UK.

Hafiz Naderi (H)

Imperial College Healthcare NHS Trust, London, UK.

Perviz Asaria (P)

Imperial College Healthcare NHS Trust, London, UK.

Nilesh Sutaria (N)

Imperial College Healthcare NHS Trust, London, UK.

Iqbal S Malik (IS)

Imperial College Healthcare NHS Trust, London, UK.

Punam A Pabari (PA)

Imperial College Healthcare NHS Trust, London, UK.

Bushra S Rana (BS)

National Heart and Lung Institute, Imperial College London, London, UK.
Imperial College Healthcare NHS Trust, London, UK.

Classifications MeSH