A Rare Case Presentation: Diagnosing Primary Biliary Cholangitis in a Male Patient With Concomitant Type 1 Diabetes.
antimitochondrial antibody
autoimmune disease
cholestyramine
liver cirrhosis
male primary biliary cholangitis
primary biliary cholangitis
pruritis
type 1 diabetes
ursodiol
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Jul 2021
Jul 2021
Historique:
accepted:
02
07
2021
entrez:
9
8
2021
pubmed:
10
8
2021
medline:
10
8
2021
Statut:
epublish
Résumé
Primary biliary cholangitis (PBC) is characterized as an autoimmune disease that involves the destruction of intrahepatic bile ducts, characteristically leading to a cholestatic liver. The presence of disease-specific antimitochondrial antibodies (AMA) is the gold standard to diagnose PBC. Typically, PBC is known to affect female populations exceedingly over their male counterparts. Associated autoimmune diseases include Sjogren's and Raynaud's syndrome, which are also more prevalent in women. The low incidence rates of men affected with PBC, especially with a concomitant type 1 diabetes diagnosis, have resulted in little being known about the clinical course of the disease in this particular population group. Current research suggests no significant histological, serological, or biochemical differences between PBC in males and females. However, some symptoms and clinical associations may be different. This case report presents the rare case of a male patient with type 1 diabetes recently diagnosed with PBC.
Identifiants
pubmed: 34367753
doi: 10.7759/cureus.16109
pmc: PMC8330503
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e16109Informations de copyright
Copyright © 2021, Johnson et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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