Case Report: Infection With SARS-CoV-2 in the Presence of High Levels of Vaccine-Induced Neutralizing Antibody Responses.
SARS-CoV-2
breakthrough infection
mRNA vaccines
neutralizing antibodies
virus variants
Journal
Frontiers in medicine
ISSN: 2296-858X
Titre abrégé: Front Med (Lausanne)
Pays: Switzerland
ID NLM: 101648047
Informations de publication
Date de publication:
2021
2021
Historique:
received:
03
05
2021
accepted:
29
06
2021
entrez:
9
8
2021
pubmed:
10
8
2021
medline:
10
8
2021
Statut:
epublish
Résumé
We present a case of SARS-CoV-2 B.1. 525 infection in a healthcare worker despite the presence of highly neutralizing, multivariant-specific antibodies 7 weeks after full vaccination with the mRNA vaccine BNT162b2. We show that the virus replicated to high levels in the upper respiratory tract over the course of several days in the presence of strong antibody responses. The virus was readily propagatable
Identifiants
pubmed: 34368197
doi: 10.3389/fmed.2021.704719
pmc: PMC8342944
doi:
Types de publication
Case Reports
Langues
eng
Pagination
704719Informations de copyright
Copyright © 2021 Schulte, Marx, Korencak, Emmert, Aldabbagh, Eis-Hübinger and Streeck.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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