Myeloid sarcoma of the colon as initial presentation in acute promyelocytic leukemia: A case report and review of the literature.
Acute promyelocytic leukemia
All-trans retinoic acid
Case report
Colon
Extramedullary disease
Fluorescent in situ hybridization
Myeloid sarcoma
Journal
World journal of clinical cases
ISSN: 2307-8960
Titre abrégé: World J Clin Cases
Pays: United States
ID NLM: 101618806
Informations de publication
Date de publication:
26 Jul 2021
26 Jul 2021
Historique:
received:
31
01
2021
revised:
07
05
2021
accepted:
26
05
2021
entrez:
9
8
2021
pubmed:
10
8
2021
medline:
10
8
2021
Statut:
ppublish
Résumé
Myeloid sarcoma (MS) rarely occurs in acute promyelocytic leukemia (APL) at onset, but it can develop in relapse cases, especially after APL treated with all-trans retinoic acid (ATRA). Therefore little is known about the clinical features and suitable treatment for APL related MS due to the rarity of the disease, although this may be different from the treatment and prognosis of MS in the relapse stage. To our best knowledge, this is the second case report of APL initial presentation as colon MS. A 77-year-old woman complained of intermittent right lower abdominal pain, black stool, and difficult defecation for 2 mo. Physical examination showed diffuse tenderness during deep palpation and an anemic appearance. Laboratory findings showed positivity for fecal occult blood testing; white blood cell count: 3.84 × 10 Early use of ATRA can benefit APL patients, regardless of whether MS is the first or recurrent manifestation.
Sections du résumé
BACKGROUND
BACKGROUND
Myeloid sarcoma (MS) rarely occurs in acute promyelocytic leukemia (APL) at onset, but it can develop in relapse cases, especially after APL treated with all-trans retinoic acid (ATRA). Therefore little is known about the clinical features and suitable treatment for APL related MS due to the rarity of the disease, although this may be different from the treatment and prognosis of MS in the relapse stage. To our best knowledge, this is the second case report of APL initial presentation as colon MS.
CASE SUMMARY
METHODS
A 77-year-old woman complained of intermittent right lower abdominal pain, black stool, and difficult defecation for 2 mo. Physical examination showed diffuse tenderness during deep palpation and an anemic appearance. Laboratory findings showed positivity for fecal occult blood testing; white blood cell count: 3.84 × 10
CONCLUSION
CONCLUSIONS
Early use of ATRA can benefit APL patients, regardless of whether MS is the first or recurrent manifestation.
Identifiants
pubmed: 34368322
doi: 10.12998/wjcc.v9.i21.6017
pmc: PMC8316963
doi:
Types de publication
Case Reports
Langues
eng
Pagination
6017-6025Informations de copyright
©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Déclaration de conflit d'intérêts
Conflict-of-interest statement: The authors declare that they have no conflict of interest to report.
Références
Clin Case Rep. 2019 Jan 08;7(2):316-321
pubmed: 30847197
Clin Lab Haematol. 1990;12(1):97-9
pubmed: 2344722
Leukemia. 2003 Jun;17(6):1100-3
pubmed: 12764375
Haematologica. 2007 Dec;92(12):1615-22
pubmed: 18055984
Am J Clin Pathol. 1984 Dec;82(6):730-4
pubmed: 6594928
Leukemia. 2007 Feb;21(2):340-50
pubmed: 17170724
Rep Pract Oncol Radiother. 2020 Mar-Apr;25(2):174-177
pubmed: 32021572
Acta Chir Belg. 1999 Apr;99(2):78-81
pubmed: 10352737
Br J Haematol. 2008 May;141(5):565
pubmed: 18373707
Acta Med Okayama. 2004 Oct;58(5):251-4
pubmed: 15666994
Turk J Haematol. 2012 Sep;29(3):278-82
pubmed: 24744674
Rev Bras Hematol Hemoter. 2011;33(6):478-80
pubmed: 23049367
Med Pediatr Oncol. 1978;4(4):289-95
pubmed: 281594
Cancer. 1994 Oct 1;74(7):1882-6
pubmed: 8082094
Korean J Hematol. 2011 Mar;46(1):52-6
pubmed: 21461306
Best Pract Res Clin Haematol. 2014 Mar;27(1):63-8
pubmed: 24907018
Hematol Oncol. 2012 Mar;30(1):34-40
pubmed: 21638303
Naika. 1970 Aug;26(2):357-62
pubmed: 5270916
J Neurosurg. 2006 Dec;105(6):912-5
pubmed: 17405265
J Clin Oncol. 2001 Oct 15;19(20):4023-8
pubmed: 11600603
Leuk Res. 2009 Apr;33(4):580-2
pubmed: 18804280
Clin Lab Haematol. 1989;11(3):288-9
pubmed: 2591162
Br J Haematol. 2003 Aug;122(4):688-9
pubmed: 12899728
Cancer Genet Cytogenet. 2005 Mar;157(2):148-50
pubmed: 15721636
Histopathology. 1999 May;34(5):391-8
pubmed: 10231412
Leukemia. 1998 Dec;12(12):2035-6
pubmed: 9844936
Leukemia. 2012 Dec;26(12):2469-73
pubmed: 22699453
Arkh Patol. 2019;81(3):59-65
pubmed: 31317932
J Community Support Oncol. 2016 Mar;14(3):126-9
pubmed: 27058871
Pediatr Blood Cancer. 2008 Mar;50(3):657-60
pubmed: 17437290
World J Gastrointest Pathophysiol. 2010 Oct 15;1(4):144-6
pubmed: 21607155
Indian J Hematol Blood Transfus. 2013 Sep;29(3):152-4
pubmed: 24426361
Int J Hematol. 2009 May;89(4):489-496
pubmed: 19340529
Ann Hematol. 2014 Feb;93(2):339-40
pubmed: 23716188
Cancer. 1998 Oct 15;83(8):1522-8
pubmed: 9781945
Head Neck. 2013 Oct;35(10):E310-3
pubmed: 22972688
Leukemia. 2006 Jan;20(1):35-41
pubmed: 16307026
Cancer. 1996 Dec 15;78(12):2510-4
pubmed: 8952559
Haematologica. 1995 Jan-Feb;80(1):44-6
pubmed: 7758990