Evaluation of the Efficacy of Doxycycline, Ciprofloxacin, Levofloxacin, and Co-trimoxazole Using


Journal

Antimicrobial agents and chemotherapy
ISSN: 1098-6596
Titre abrégé: Antimicrob Agents Chemother
Pays: United States
ID NLM: 0315061

Informations de publication

Date de publication:
18 10 2021
Historique:
pubmed: 10 8 2021
medline: 3 11 2021
entrez: 9 8 2021
Statut: ppublish

Résumé

Q fever, caused by the intracellular pathogen Coxiella burnetii, is traditionally treated using tetracycline antibiotics, such as doxycycline. Doxycycline is often poorly tolerated, and antibiotic-resistant strains have been isolated. In this study, we have evaluated a panel of antibiotics (doxycycline, ciprofloxacin, levofloxacin, and co-trimoxazole) against C. burnetii using

Identifiants

pubmed: 34370577
doi: 10.1128/AAC.00673-21
pmc: PMC8522727
doi:

Substances chimiques

Anti-Bacterial Agents 0
Ciprofloxacin 5E8K9I0O4U
Levofloxacin 6GNT3Y5LMF
Trimethoprim, Sulfamethoxazole Drug Combination 8064-90-2
Doxycycline N12000U13O

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0067321

Subventions

Organisme : MOD | Defence Science and Technology Laboratory (Dstl)

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Auteurs

K A Clay (KA)

Academic Department, Royal Centre for Defence Medicine (Academia and Research), Birmingham, United Kingdom.
CBR Division, Defence Science and Technology Laboratorygrid.417845.b (Dstl), Porton Down, Salisbury, Wiltshire, United Kingdom.

M G Hartley (MG)

CBR Division, Defence Science and Technology Laboratorygrid.417845.b (Dstl), Porton Down, Salisbury, Wiltshire, United Kingdom.

S Armstrong (S)

CBR Division, Defence Science and Technology Laboratorygrid.417845.b (Dstl), Porton Down, Salisbury, Wiltshire, United Kingdom.

K R Bewley (KR)

Public Health Englandgrid.271308.f, Porton Down, Salisbury, Wiltshire, United Kingdom.

K Godwin (K)

Public Health Englandgrid.271308.f, Porton Down, Salisbury, Wiltshire, United Kingdom.

E Rayner (E)

Public Health Englandgrid.271308.f, Porton Down, Salisbury, Wiltshire, United Kingdom.

J Vipond (J)

Public Health Englandgrid.271308.f, Porton Down, Salisbury, Wiltshire, United Kingdom.

M Bailey (M)

Academic Department, Royal Centre for Defence Medicine (Academia and Research), Birmingham, United Kingdom.

T P Atkins (TP)

CBR Division, Defence Science and Technology Laboratorygrid.417845.b (Dstl), Porton Down, Salisbury, Wiltshire, United Kingdom.
College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom.

I H Norville (IH)

CBR Division, Defence Science and Technology Laboratorygrid.417845.b (Dstl), Porton Down, Salisbury, Wiltshire, United Kingdom.

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Classifications MeSH