Dietary Intake of Flaxseed Oil since Early Stages of Life Promotes Femur Quality in Male Rats.
dual-energy X-ray absorptiometry
femur
flaxseed oil
rats
Journal
Journal of the American Nutrition Association
ISSN: 2769-707X
Titre abrégé: J Am Nutr Assoc
Pays: United States
ID NLM: 9918300687506676
Informations de publication
Date de publication:
07 2022
07 2022
Historique:
pubmed:
10
8
2021
medline:
22
7
2022
entrez:
9
8
2021
Statut:
ppublish
Résumé
Flaxseed oil (FO) is an alpha linolenic acid source important for growth and body development. However, there is little literature on the role of FO in critical stages of bone development and formation. This study evaluated the influence of a diet containing FO on rat femurs. After birth, mothers and pups were divided into control and flaxseed groups (n = 6 pups each) fed diets containing 7% soybean oil (C) or 7% FO. At 21 days, pups were weaned and separated from the mothers, and control or experimental diets were continued. At 67 days, the following were analyzed: osteocalcin and osteoprotegerin (OPG) levels, bone mineral density (BMD) and content, and bone area; the dimension, BMD, head radiodensity, and biomechanical proprieties of the right femur; and histomorphometric parameters of the left femur. Compared to the C group, the FO group presented ( The FO diet contributed to femur quality in healthy male Wistar rats.
Sections du résumé
BACKGROUND
Flaxseed oil (FO) is an alpha linolenic acid source important for growth and body development. However, there is little literature on the role of FO in critical stages of bone development and formation.
OBJECTIVE
This study evaluated the influence of a diet containing FO on rat femurs.
METHODS
After birth, mothers and pups were divided into control and flaxseed groups (n = 6 pups each) fed diets containing 7% soybean oil (C) or 7% FO. At 21 days, pups were weaned and separated from the mothers, and control or experimental diets were continued. At 67 days, the following were analyzed: osteocalcin and osteoprotegerin (OPG) levels, bone mineral density (BMD) and content, and bone area; the dimension, BMD, head radiodensity, and biomechanical proprieties of the right femur; and histomorphometric parameters of the left femur.
RESULTS
Compared to the C group, the FO group presented (
CONCLUSION
The FO diet contributed to femur quality in healthy male Wistar rats.
Identifiants
pubmed: 34370629
doi: 10.1080/07315724.2021.1912673
doi:
Substances chimiques
Osteocalcin
104982-03-8
Linseed Oil
8001-26-1
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM