Screening for Hepatocellular Carcinoma in Patients with Hepatitis B.


Journal

Viruses
ISSN: 1999-4915
Titre abrégé: Viruses
Pays: Switzerland
ID NLM: 101509722

Informations de publication

Date de publication:
08 07 2021
Historique:
received: 15 06 2021
revised: 05 07 2021
accepted: 05 07 2021
entrez: 10 8 2021
pubmed: 11 8 2021
medline: 15 12 2021
Statut: epublish

Résumé

Chronic hepatitis B (CHB) infection is a significant risk factor for developing hepatocellular carcinoma (HCC). As HCC is associated with significant morbidity and mortality, screening patients with CHB at a high risk for HCC is recommended in an attempt to improve these outcomes. However, the screening recommendations on who to screen and how often are not uniform. Identifying patients at the highest risk of HCC would allow for the best use of health resources. In this review, we evaluate the literature on screening patients with CHB for HCC, strategies for optimizing adherence to screening, and potential risk stratification tools to identify patients with CHB at a high risk of developing HCC.

Identifiants

pubmed: 34372524
pii: v13071318
doi: 10.3390/v13071318
pmc: PMC8310362
pii:
doi:

Substances chimiques

Antiviral Agents 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NCI NIH HHS
ID : K08 CA222676
Pays : United States

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Auteurs

Yashasavi Sachar (Y)

London Health Sciences Center, Department of Medicine, Division of Gastroenterology, Western University, London, ON N6A 5A5, Canada.

Mayur Brahmania (M)

London Health Sciences Center, Department of Medicine, Division of Gastroenterology, Western University, London, ON N6A 5A5, Canada.
Centre for Quality, Innovation and Safety, Schulich School of Medicine & Dentistry, Western University, London, ON N6A 5W9, Canada.

Renumathy Dhanasekaran (R)

Department of Medicine, Division of Gastroenterology and Hepatology, Stanford University, Stanford, CA 94305, USA.

Stephen E Congly (SE)

Department of Medicine, Division of Gastroenterology and Hepatology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4Z6, Canada.
O'Brien Institute of Public Health, University of Calgary, Calgary, AB T2N 4Z6, Canada.

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