Juvenile Angiofibroma: What Is on Stage?


Journal

The Laryngoscope
ISSN: 1531-4995
Titre abrégé: Laryngoscope
Pays: United States
ID NLM: 8607378

Informations de publication

Date de publication:
06 2022
Historique:
revised: 09 07 2021
received: 01 05 2021
accepted: 26 07 2021
pubmed: 11 8 2021
medline: 18 5 2022
entrez: 10 8 2021
Statut: ppublish

Résumé

The aim of the present study is to validate and compare four of the most widely used staging systems for juvenile angiofibroma on a homogeneous cohort of patients. Retrospective case series. A retrospective review of patients treated with endoscopic or endoscopic-assisted surgical resection between 1999 and 2020 was carried out. Each case was classified according to the following staging systems: Andrews-Fisch (1989), Radkowski (1996), University of Pittsburgh Medical Center (2010), and Janakiram (2017). Spearman's rank correlation test and areas under the curve of receiver operator curves were used to assess the correlation between outcomes of interests (blood loss, surgical time, need for transfusion, and persistence of disease) and stage of disease. Seventy-nine patients were included, with a median follow-up time of 25 months (range 12-127 months). Median surgical time was 217 minutes (range 52-625). Median blood loss was 500 mL (range 40-5200) and 27 patients (34.2%) required blood transfusions. Seven patients (8.9%) showed persistence of disease. All classification systems showed a similar association with blood loss, surgical time, persistence of disease, and need for transfusion. Involvement of the infratemporal fossa and intracranial extension was identified as red flags for surgical planning and preoperative counseling, as associated with increased risk for transfusion and persistent/recurrent disease, respectively. No classification system was found to be better than the others in predicting the most important outcomes. Therefore, the simplest and most easily applicable system would be the preferred one to be used in clinical practice. 4 Laryngoscope, 132:1160-1165, 2022.

Identifiants

pubmed: 34374999
doi: 10.1002/lary.29801
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1160-1165

Informations de copyright

© 2021 The American Laryngological, Rhinological and Otological Society, Inc.

Références

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Auteurs

Maurizio Bignami (M)

Department of Otorhinolaryngology, Department of Surgery, ASST Lariana, University of Insubria, Como, Italy.
Head and Neck Surgery & Forensic Dissection Research Center (HNS&FDRc), Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy.

Giacomo Pietrobon (G)

Department of Head and Neck Surgery and Otorhinolaryngology, European Institute of Oncology IRCCS, Milan, Italy.

Alberto D Arosio (AD)

Division of Otorhinolaryngology, Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy.
Division of Otorhinolaryngology, Department of Surgical Specialties, ASST Sette Laghi, Ospedale di Circolo, Varese, Italy.

Enrico Fazio (E)

Division of Otorhinolaryngology, Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy.

Larissa Nocchi Cardim (L)

Department of Radiology, ASST Sette Laghi, Del Ponte Hospital, Varese, Italy.
Department of Neuroradiology, ASST Sette Laghi, Circolo Hospital, Varese, Italy.

Sabina Strocchi (S)

Medical Physics Department, ASST Sette Laghi, Varese, Italy.

Stefano Molinaro (S)

Department of Neuroradiology, ASST Sette Laghi, Circolo Hospital, Varese, Italy.

Edoardo Agosti (E)

Division of Neurosurgery, Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy.

Apostolos Karligkiotis (A)

Head and Neck Surgery & Forensic Dissection Research Center (HNS&FDRc), Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy.
Division of Otorhinolaryngology, Department of Surgical Specialties, ASST Sette Laghi, Ospedale di Circolo, Varese, Italy.

Paolo Battaglia (P)

Head and Neck Surgery & Forensic Dissection Research Center (HNS&FDRc), Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy.
Division of Otorhinolaryngology, Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy.
Division of Otorhinolaryngology, Department of Surgical Specialties, ASST Sette Laghi, Ospedale di Circolo, Varese, Italy.

Paolo Castelnuovo (P)

Head and Neck Surgery & Forensic Dissection Research Center (HNS&FDRc), Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy.
Division of Otorhinolaryngology, Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy.
Division of Otorhinolaryngology, Department of Surgical Specialties, ASST Sette Laghi, Ospedale di Circolo, Varese, Italy.

Andrea Giorgianni (A)

Department of Neuroradiology, ASST Sette Laghi, Circolo Hospital, Varese, Italy.

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