Lessons learned from SARS-CoV-2 measurements in wastewater.
Concentration
Detection
SARS-CoV-2
Sampling
Wastewater
Wastewater based surveillance
Journal
The Science of the total environment
ISSN: 1879-1026
Titre abrégé: Sci Total Environ
Pays: Netherlands
ID NLM: 0330500
Informations de publication
Date de publication:
01 Dec 2021
01 Dec 2021
Historique:
received:
09
05
2021
revised:
16
07
2021
accepted:
17
07
2021
pubmed:
11
8
2021
medline:
1
10
2021
entrez:
10
8
2021
Statut:
ppublish
Résumé
Standardized protocols for wastewater-based surveillance (WBS) for the RNA of SARS-CoV-2, the virus responsible for the current COVID-19 pandemic, are being developed and refined worldwide for early detection of disease outbreaks. We report here on lessons learned from establishing a WBS program for SARS-CoV-2 integrated with a human surveillance program for COVID-19. We have established WBS at three campuses of a university, including student residential dormitories and a hospital that treats COVID-19 patients. Lessons learned from this WBS program address the variability of water quality, new detection technologies, the range of detectable viral loads in wastewater, and the predictive value of integrating environmental and human surveillance data. Data from our WBS program indicated that water quality was statistically different between sewer sampling sites, with more variability observed in wastewater coming from individual buildings compared to clusters of buildings. A new detection technology was developed based upon the use of a novel polymerase called V2G. Detectable levels of SARS-CoV-2 in wastewater varied from 10
Identifiants
pubmed: 34375259
pii: S0048-9697(21)04250-9
doi: 10.1016/j.scitotenv.2021.149177
pmc: PMC8294117
pii:
doi:
Substances chimiques
RNA, Viral
0
Waste Water
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
149177Subventions
Organisme : NIAID NIH HHS
ID : P30 AI073961
Pays : United States
Organisme : NIDA NIH HHS
ID : U01 DA053941
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR002736
Pays : United States
Informations de copyright
Copyright © 2021 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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