High resolution flat-panel CT arthrography vs. MR arthrography of artificially created osteochondral defects in ex vivo upper ankle joints.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2021
Historique:
received: 08 06 2021
accepted: 20 07 2021
entrez: 10 8 2021
pubmed: 11 8 2021
medline: 27 11 2021
Statut: epublish

Résumé

High resolution flat-panel computed tomography arthrography (FPCT-A) and magnetic resonance arthrography (MR-A) are well suited to evaluate osteochondral lesions. The current study compares the performance of FPCT-A versus MR-A in an experimental setting. Fourteen cadaveric ankles were prepared with artificial osteochondral defects of various sizes in four separate talar locations. After intra-articular contrast injection, FPCT-A and 3-T MR-A were acquired. Each defect was then filled with synthetic pallets. The resulting cast was used as reference. Two independent radiologists measured the dimensions of all defects with FPCT-A and MR-A. Intra-class correlation coefficients (ICC) were calculated. Data were compared using t-tests and Bland-Altman plots. The correlation for FPCT-A and cast was higher compared to MR-A and cast (ICC 0.876 vs. 0.799 for surface [length x width]; ICC 0.887 vs. 0.866 for depth, p<0.001). Mean differences between FPCT-A and cast measurements were -1.1 mm for length (p<0.001), -0.7 mm for width (p<0.001) and -0.4 mm for depth (p = 0.023). By MR-A, there were no significant differences for length and width compared to cast (p>0.05). Depth measurements were significantly smaller by MR-A (mean difference -1.1 mm, p<0.001). There was no bias between the different modalities. Ex vivo FPCT-A and MR-A both deliver high diagnostic accuracy for the evaluation of osteochondral defects. FPCT-A was slightly more accurate than MR-A, which was most significant when measuring lesion depth.

Identifiants

pubmed: 34375344
doi: 10.1371/journal.pone.0255616
pii: PONE-D-21-18448
pmc: PMC8354460
doi:

Types de publication

Comparative Study Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0255616

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

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Auteurs

Gesa H Pöhler (GH)

Department of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.

Lena Sonnow (L)

Department of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.

Sarah Ettinger (S)

Department of Orthopedic Surgery, Hannover Medical School at Diakovere Annastift, Hannover, Germany.

Alexandra Rahn (A)

Department of Orthopedic Surgery, Hannover Medical School at Diakovere Annastift, Hannover, Germany.

Filip Klimes (F)

Department of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.

Christoph Becher (C)

International Centrum for Hip, Knee and Foot Surgery, ATOS Clinic Heidelberg, Heidelberg, Germany.

Christian von Falck (C)

Department of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.

Frank K Wacker (FK)

Department of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.

Christian Plaass (C)

Department of Orthopedic Surgery, Hannover Medical School at Diakovere Annastift, Hannover, Germany.

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