Stimulation of an immune system by different types of allergens causes seasonal (late spring and summer) factors to increase probability of allergic rhinitis symptoms. The Epidemiology of Allergic Diseases in Poland (ECAP) survey: part two.
ECAP
allergic rhinitis
asthma
epidemiology
specific IgE
Journal
Postepy dermatologii i alergologii
ISSN: 1642-395X
Titre abrégé: Postepy Dermatol Alergol
Pays: Poland
ID NLM: 101168357
Informations de publication
Date de publication:
Jun 2021
Jun 2021
Historique:
received:
21
11
2019
accepted:
01
12
2019
entrez:
11
8
2021
pubmed:
12
8
2021
medline:
12
8
2021
Statut:
ppublish
Résumé
Specific immunoglobulins E (sIgE) are important parameters to estimate severity of allergic diseases. To determine the relationship between the concentration of sIgE antibodies in serum and clinical outcome of allergic diseases. The concentration of sIgE antibodies against allergens Dermatophagoides pteronyssinus, cat dander, Timothy grass, Alternaria alternata were determined in serum of 4077 respondents randomly selected from 9 regions (ECAP study). Positive results of sIgE (≥ 0.35 IU/ml) were correlated with answers in ECRHSII and ISAAC questionnaires. IgE antibodies are more frequently detected in respondents aged over 4 years when they had their first attack of asthma (cat dander The first attack of asthma appears later mainly in patients whose immune systems are more strongly stimulated by allergens. Development of allergic rhinitis in patients aged over 29 years presumably needs weaker stimulation of their immune systems by allergens than in patients aged 0-19 years. Stimulation of an immune system by different types of allergens modifies its response in such a way that seasonal (late spring and summer) factors increase probability of allergic rhinitis symptoms.
Identifiants
pubmed: 34377117
doi: 10.5114/ada.2021.107925
pii: 107925
pmc: PMC8330865
doi:
Types de publication
Journal Article
Langues
eng
Pagination
384-388Informations de copyright
Copyright: © 2021 Termedia Sp. z o. o.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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