Insights into the modulation of the interferon response and NAD

Antiviral Agents / therapeutic use COVID-19 Humans Interferons / therapeutic use NAD Pandemics SARS-CoV-2
Innate immune system SARS-CoV-2 mitochondrial dysfunction nicotinamide adenine dinucleotide

Journal

International reviews of immunology
ISSN: 1563-5244
Titre abrégé: Int Rev Immunol
Pays: England
ID NLM: 8712260

Informations de publication

Date de publication:
2022
Historique:
pubmed: 12 8 2021
medline: 15 7 2022
entrez: 11 8 2021
Statut: ppublish

Résumé

The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in dramatic worldwide mortality. Along with developing vaccines, the medical profession is exploring new strategies to curb this pandemic. A better understanding of the molecular consequences of SARS-CoV-2 cellular infection could lead to more effective and safer treatments. This review discusses the potential underlying impact of SARS-CoV-2 in modulating interferon (IFN) secretion and in causing mitochondrial NAD

Identifiants

DOI: 10.1080/08830185.2021.1961768 PMID: 34378474
pubmed: 34378474
doi: 10.1080/08830185.2021.1961768
doi:

Substances chimiques

Antiviral Agents 0
NAD 0U46U6E8UK
Interferons 9008-11-1

Types de publication

Journal Article Review Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

464-474

Auteurs

Nada J Habeichi (NJ)

Department of Pharmacology and Toxicology, American University of Beirut Faculty of Medicine, Beirut, Lebanon.
Department of Signaling and Cardiovascular Pathophysiology, Université Paris-Saclay, Inserm, UMR-S 1180, Châtenay-Malabry, France.

Cynthia Tannous (C)

Department of Pharmacology and Toxicology, American University of Beirut Faculty of Medicine, Beirut, Lebanon.

Andriy Yabluchanskiy (A)

Center for Geroscience and Healthy Brain Aging, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.

Raffaele Altara (R)

Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
KG Jebsen Center for Cardiac Research, Oslo, Norway.
Department of Pathology, School of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.

Mathias Mericskay (M)

Department of Signaling and Cardiovascular Pathophysiology, Université Paris-Saclay, Inserm, UMR-S 1180, Châtenay-Malabry, France.

George W Booz (GW)

Department of Pharmacology and Toxicology, School of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.

Fouad A Zouein (FA)

Department of Pharmacology and Toxicology, American University of Beirut Faculty of Medicine, Beirut, Lebanon.
ORCID: 0000-0003-4451-804X

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antiviraux › Insights into the modulation of the interferon...
questionsmedicales.fr › Maladies de l'appareil respiratoire › Infections de l'appareil respiratoire › Pneumopathie infectieuse › Pneumopathie virale › COVID-19 › Insights into the modulation of the interferon...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Insights into the modulation of the interferon...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Interférons › Insights into the modulation of the interferon...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Nucléotides › Ribonucléotides › Nucléotides adényliques › NAD › Insights into the modulation of the interferon...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Épidémies de maladies › Épidémies › Pandémies › Insights into the modulation of the interferon...
questionsmedicales.fr › Virus › Virus à ARN › Virus à ARN à brin positif › Nidovirales › Coronaviridae › Coronavirus › Betacoronavirus › Virus du SRAS › SARS-CoV-2 › Insights into the modulation of the interferon...