Fabrication techniques involved in developing the composite scaffolds PCL/HA nanoparticles for bone tissue engineering applications.
Biocompatible Materials
/ chemistry
Bone Regeneration
Bone and Bones
/ metabolism
Durapatite
/ chemistry
Freeze Drying
Humans
Materials Testing
Nanoparticles
/ chemistry
Osteoblasts
/ drug effects
Phase Transition
Polyesters
/ chemistry
Porosity
Regeneration
Solvents
/ chemistry
Stress, Mechanical
Tissue Engineering
/ methods
Tissue Scaffolds
/ chemistry
Journal
Journal of materials science. Materials in medicine
ISSN: 1573-4838
Titre abrégé: J Mater Sci Mater Med
Pays: United States
ID NLM: 9013087
Informations de publication
Date de publication:
11 Aug 2021
11 Aug 2021
Historique:
received:
21
09
2020
accepted:
28
05
2021
entrez:
11
8
2021
pubmed:
12
8
2021
medline:
27
1
2022
Statut:
epublish
Résumé
A fine-tuned combination of scaffolds, biomolecules, and mesenchymal stem cells (MSCs) is used in tissue engineering to restore the function of injured bone tissue and overcome the complications associated with its regeneration. For two decades, biomaterials have attracted much interest in mimicking the native extracellular matrix of bone tissue. To this aim, several approaches based on biomaterials combined with MSCs have been amply investigated. Recently, hydroxyapatite (HA) nanoparticles have been incorporated with polycaprolactone (PCL) matrix as a suitable substitute for bone tissue engineering applications. This review article aims at providing a brief overview on PCL/HA composite scaffold fabrication techniques such as sol-gel, rapid prototyping, electro-spinning, particulate leaching, thermally induced phase separation, and freeze-drying, as suitable approaches for tailoring morphological, mechanical, and biodegradability properties of the scaffolds for bone tissues. Among these methods, the 3D plotting method shows improvements in pore architecture (pore size of ≥600 µm and porosity of 92%), mechanical properties (higher than 18.38 MPa), biodegradability, and good bioactivity in bone tissue regeneration.
Identifiants
pubmed: 34379204
doi: 10.1007/s10856-021-06564-0
pii: 10.1007/s10856-021-06564-0
pmc: PMC8357662
doi:
Substances chimiques
Biocompatible Materials
0
Polyesters
0
Solvents
0
polycaprolactone
24980-41-4
Durapatite
91D9GV0Z28
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
93Informations de copyright
© 2021. The Author(s).
Références
Biomaterials. 2002 Dec;23(23):4437-47
pubmed: 12322962
Int J Oral Maxillofac Surg. 2008 Oct;37(10):929-34
pubmed: 18768295
Materials (Basel). 2017 Sep 22;10(10):
pubmed: 28937605
Am J Sports Med. 2018 Mar;46(4):995-999
pubmed: 28423287
Methods Mol Med. 1999;18:47-56
pubmed: 21370166
J Biomed Mater Res A. 2008 Jun 15;85(4):938-53
pubmed: 17896770
J Oral Maxillofac Surg. 2012 Apr;70(4):972-82
pubmed: 21763048
Angiogenesis. 2011 Mar;14(1):47-59
pubmed: 21104120
Acta Biomater. 2010 Jun;6(6):2020-7
pubmed: 20004748
Biomed Microdevices. 2013 Apr;15(2):369-79
pubmed: 23324877
Biomaterials. 2005 Jun;26(18):3961-71
pubmed: 15626443
J Mater Sci Mater Med. 2003 May;14(5):443-50
pubmed: 15348448
Biomaterials. 2007 Apr;28(12):2109-21
pubmed: 17258315
Ann Med. 2008;40(4):268-80
pubmed: 18428020
J Mater Sci Mater Med. 2010 Jan;21(1):343-51
pubmed: 19653069
Biomaterials. 2006 Dec;27(35):5892-900
pubmed: 16945409
Biomaterials. 2005 Sep;26(27):5474-91
pubmed: 15860204
Methods. 2016 Apr 15;99:62-8
pubmed: 26384580
J Biomater Sci Polym Ed. 2014;25(17):1986-2008
pubmed: 25291106
Adv Drug Deliv Rev. 2008 Jan 14;60(2):184-98
pubmed: 18045729
Mater Sci Eng C Mater Biol Appl. 2017 Sep 1;78:1246-1262
pubmed: 28575964
Tissue Eng. 2001 Dec;7(6):679-89
pubmed: 11749726
Curr Stem Cell Res Ther. 2008 Dec;3(4):254-64
pubmed: 19075755
J Mater Sci Mater Med. 2013 Aug;24(8):1843-51
pubmed: 23712535
Biomaterials. 2008 May;29(13):2096-103
pubmed: 18289666
ANZ J Surg. 2001 Jun;71(6):354-61
pubmed: 11409021
PLoS One. 2014 Jan 27;9(1):e85871
pubmed: 24475056
ACS Appl Mater Interfaces. 2012 Mar;4(3):1490-9
pubmed: 22296410
Crit Rev Biomed Eng. 2012;40(5):363-408
pubmed: 23339648
Nanotechnology. 2004 Jan 1;15(1):
pubmed: 34911207
Biomed Mater. 2007 Jun;2(2):142-50
pubmed: 18458448
J Biomater Sci Polym Ed. 2010;21(6-7):951-62
pubmed: 20482995
Sci Rep. 2018 Jun 11;8(1):8907
pubmed: 29891842
Biomaterials. 2016 Oct;104:323-38
pubmed: 27475728
Biomaterials. 2002 Feb;23(4):1169-85
pubmed: 11791921
J Biomed Mater Res A. 2007 Nov;83(2):434-45
pubmed: 17465019
Acta Biomater. 2010 Oct;6(10):4090-9
pubmed: 20417736
J Nanosci Nanotechnol. 2006 Feb;6(2):514-22
pubmed: 16573054
J Biomater Sci Polym Ed. 2017 Sep;28(13):1256-1270
pubmed: 28598722
Science. 1993 May 14;260(5110):920-6
pubmed: 8493529
Bioprocess Biosyst Eng. 2011 May;34(4):505-13
pubmed: 21170553
J Biomech Eng. 2009 Nov;131(11):111002
pubmed: 20353253
J Biomed Mater Res A. 2010 Mar 1;92(3):997-1006
pubmed: 19296544
J R Soc Interface. 2010 Feb 6;7(43):209-27
pubmed: 19864265
Biomed Res Int. 2014;2014:321549
pubmed: 24868523
Acta Biomater. 2014 Jun;10(6):2341-53
pubmed: 24556448
Acta Biomater. 2007 Nov;3(6):1007-18
pubmed: 17627910
Int J Pharm. 2017 May 25;523(2):441-453
pubmed: 27640245
ASAIO J. 2002 Sep-Oct;48(5):460-4
pubmed: 12296562
Biomaterials. 2007 Dec;28(35):5291-7
pubmed: 17884162
Indian J Med Res. 2015 Dec;142(6):747-58
pubmed: 26831424
Expert Rev Med Devices. 2006 Nov;3(6):835-51
pubmed: 17280547
Biomaterials. 2001 Jul;22(13):1721-30
pubmed: 11396875
Acta Biomater. 2010 Jul;6(7):2511-7
pubmed: 19616649
J Biomed Mater Res A. 2010 Jul;94(1):241-51
pubmed: 20166220
Med Biol Eng Comput. 1992 Jul;30(4):CE8-12
pubmed: 1487936
Expert Rev Med Devices. 2005 May;2(3):303-17
pubmed: 16288594
PLoS One. 2011;6(10):e26211
pubmed: 22022571
Mayo Clin Proc. 2009 Oct;84(10):893-902
pubmed: 19797778
J Tissue Eng Regen Med. 2007 Jul-Aug;1(4):261-73
pubmed: 18038416
Materials (Basel). 2016 Dec 07;9(12):
pubmed: 28774113
ACS Appl Mater Interfaces. 2014 Sep 10;6(17):14952-63
pubmed: 25133309
J Biomed Mater Res A. 2008 Mar 1;84(3):702-9
pubmed: 17635029