EBiSC best practice: How to ensure optimal generation, qualification, and distribution of iPSC lines.


Journal

Stem cell reports
ISSN: 2213-6711
Titre abrégé: Stem Cell Reports
Pays: United States
ID NLM: 101611300

Informations de publication

Date de publication:
10 08 2021
Historique:
received: 17 11 2020
revised: 07 07 2021
accepted: 07 07 2021
entrez: 11 8 2021
pubmed: 12 8 2021
medline: 15 3 2022
Statut: ppublish

Résumé

Disease-relevant human induced pluripotent stem cells (iPSCs) are generated worldwide for research purposes; however, without robust and practical ethical, legal, and quality standards, there is a high risk that their true potential will not be realized. Best practices for tissue procurement, iPSC reprogramming, day-to-day cultivation, quality control, and data management aligned with an ethical and legal framework must be included into daily operations to ensure their promise is maximized. Here we discuss key learning experiences from 7 years of operating the European Bank for induced Pluripotent Stem Cells (EBiSC) and recommend how to incorporate solutions into a daily management framework.

Identifiants

pubmed: 34380020
pii: S2213-6711(21)00375-1
doi: 10.1016/j.stemcr.2021.07.009
pmc: PMC8365092
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1853-1867

Informations de copyright

Copyright © 2021 Fraunhofer Institut fû¥r Biomedizinische Technik. Published by Elsevier Inc. All rights reserved.

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Auteurs

Rachel Steeg (R)

Fraunhofer UK Research Ltd, Glasgow, UK.

Sabine C Mueller (SC)

Fraunhofer Institute for Biomedical Engineering (IBMT), Joseph-von-Fraunhofer-Weg 1, 66280 Sulzbach, Germany.

Nancy Mah (N)

Fraunhofer Institute for Biomedical Engineering (IBMT), Joseph-von-Fraunhofer-Weg 1, 66280 Sulzbach, Germany.

Bjørn Holst (B)

Bioneer A/S, Kogle Alle 2, 2970 Hørsholm, Denmark.

Alfredo Cabrera-Socorro (A)

Neuroscience Department, Janssen Research and Development, Turnhoutseweg 30, 2340 Beerse, Belgium.

Glyn N Stacey (GN)

International Stem Cell Banking Initiative, 2 High Street, Barley, Herts SG88HZ, UK; National Stem Cell Resource Centre, Institute of Zoology, Chinese Academy of Sciences, Beijing 100190, China; Innovation Academy for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China.

Paul A De Sousa (PA)

Paul A. De Sousa, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh EH16 4SB, UK.

Aidan Courtney (A)

KWWK Ltd, Edinburgh, UK.

Heiko Zimmermann (H)

Fraunhofer Institute for Biomedical Engineering (IBMT), Joseph-von-Fraunhofer-Weg 1, 66280 Sulzbach, Germany; Molecular and Cellular Biotechnology/Nanotechnology, Saarland University, 66123 Saarbrücken, Germany; Facultad de Ciencias del Mar, Universidad Católica del Norte, Coquimbo, Chile. Electronic address: heiko.zimmermann@ibmt.fraunhofer.de.

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