Regulation of bone phosphorus retention and bone development possibly by related hormones and local bone-derived regulators in broiler chicks.
Bone
Broiler chicken
Hormone
Local bone-derived regulator
Phosphorus
Journal
Journal of animal science and biotechnology
ISSN: 1674-9782
Titre abrégé: J Anim Sci Biotechnol
Pays: England
ID NLM: 101581293
Informations de publication
Date de publication:
12 Aug 2021
12 Aug 2021
Historique:
received:
08
03
2021
accepted:
02
06
2021
entrez:
12
8
2021
pubmed:
13
8
2021
medline:
13
8
2021
Statut:
epublish
Résumé
Phosphorus is essential for bone mineralization in broilers, however, the underlying mechanisms remain unclear. We aimed to investigate whether bone phosphorus retention and bone development might be regulated by related hormones and local bone-derived regulators in broilers. Broilers were fed diets containing different levels of non-phytate phosphorus (NPP) 0.15%, 0.25%, 0.35%, 0.45% and 0.55% or 0.15%, 0.22%, 0.29%, 0.36% and 0.43% from 1 to 21 or 22 to 42 days of age. Serum and tibia samples were collected for determinations of bone phosphorus retention and bone development parameters, related hormones and local bone-derived regulators of broiler chickens on d 14, 28 and 42, respectively. Tibia ash phosphorus, total phosphorus accumulation in tibia ash (TP These results suggested that bone phosphorus retention and bone development parameters had moderate to strong correlations with serum PTH and 1,25(OH)
Sections du résumé
BACKGROUND
BACKGROUND
Phosphorus is essential for bone mineralization in broilers, however, the underlying mechanisms remain unclear. We aimed to investigate whether bone phosphorus retention and bone development might be regulated by related hormones and local bone-derived regulators in broilers.
METHODS
METHODS
Broilers were fed diets containing different levels of non-phytate phosphorus (NPP) 0.15%, 0.25%, 0.35%, 0.45% and 0.55% or 0.15%, 0.22%, 0.29%, 0.36% and 0.43% from 1 to 21 or 22 to 42 days of age. Serum and tibia samples were collected for determinations of bone phosphorus retention and bone development parameters, related hormones and local bone-derived regulators of broiler chickens on d 14, 28 and 42, respectively.
RESULTS
RESULTS
Tibia ash phosphorus, total phosphorus accumulation in tibia ash (TP
CONCLUSIONS
CONCLUSIONS
These results suggested that bone phosphorus retention and bone development parameters had moderate to strong correlations with serum PTH and 1,25(OH)
Identifiants
pubmed: 34380559
doi: 10.1186/s40104-021-00610-1
pii: 10.1186/s40104-021-00610-1
pmc: PMC8359065
doi:
Types de publication
Journal Article
Langues
eng
Pagination
88Subventions
Organisme : the Key Program of the National Natural Science Foundation of China
ID : 31630073
Organisme : the National Key R&D Program of China
ID : 2017YFD0502200
Organisme : the China Agriculture Research System
ID : CARS-41
Organisme : the Agricultural Science and Technology Innovation Program
ID : ASTIP-IAS09
Informations de copyright
© 2021. The Author(s).
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