Discovery of an Unexpected 1,4-Oxazepine-Linked

Candida albicans Cell Line, Tumor Dimerization Gene Silencing Humans Micromonospora / enzymology Molecular Structure Oxazepines / chemistry Oxidoreductases / genetics Polyketides / chemistry

Journal

Journal of natural products
ISSN: 1520-6025
Titre abrégé: J Nat Prod
Pays: United States
ID NLM: 7906882

Informations de publication

Date de publication:
27 08 2021
Historique:
pubmed: 13 8 2021
medline: 15 12 2021
entrez: 12 8 2021
Statut: ppublish

Résumé

Fluostatins belong to the atypical angucyclinone aromatic polyketides featuring a distinctive tetracyclic benzo[

Identifiants

DOI: 10.1021/acs.jnatprod.1c00461 PMID: 34384027
pubmed: 34384027
doi: 10.1021/acs.jnatprod.1c00461
doi:

Substances chimiques

Oxazepines 0
Polyketides 0
Oxidoreductases EC 1.-

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2336-2344

Auteurs

Chunshuai Huang (C)

Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, Innovation Academy of South China Sea Ecology and Environmental Engineering, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, China.
University of Chinese Academy of Sciences, 19 Yuquan Road, Beijing 100049, China.

Chunfang Yang (C)

Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, Innovation Academy of South China Sea Ecology and Environmental Engineering, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, China.
University of Chinese Academy of Sciences, 19 Yuquan Road, Beijing 100049, China.
Sanya Institute of Oceanology, SCSIO, Yazhou Scientific Bay, Sanya 572000, China.
Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), 1119 Haibin Road, Nansha District, Guangzhou 511458, China.

Wenjun Zhang (W)

Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, Innovation Academy of South China Sea Ecology and Environmental Engineering, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, China.
University of Chinese Academy of Sciences, 19 Yuquan Road, Beijing 100049, China.
Sanya Institute of Oceanology, SCSIO, Yazhou Scientific Bay, Sanya 572000, China.
Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), 1119 Haibin Road, Nansha District, Guangzhou 511458, China.
ORCID: 0000-0002-2677-3752

Liping Zhang (L)

Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, Innovation Academy of South China Sea Ecology and Environmental Engineering, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, China.
Sanya Institute of Oceanology, SCSIO, Yazhou Scientific Bay, Sanya 572000, China.
Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), 1119 Haibin Road, Nansha District, Guangzhou 511458, China.

Yiguang Zhu (Y)

Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, Innovation Academy of South China Sea Ecology and Environmental Engineering, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, China.
University of Chinese Academy of Sciences, 19 Yuquan Road, Beijing 100049, China.
Sanya Institute of Oceanology, SCSIO, Yazhou Scientific Bay, Sanya 572000, China.
Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), 1119 Haibin Road, Nansha District, Guangzhou 511458, China.
ORCID: 0000-0001-8737-8898

Changsheng Zhang (C)

Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, Innovation Academy of South China Sea Ecology and Environmental Engineering, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, China.
University of Chinese Academy of Sciences, 19 Yuquan Road, Beijing 100049, China.
Sanya Institute of Oceanology, SCSIO, Yazhou Scientific Bay, Sanya 572000, China.
Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), 1119 Haibin Road, Nansha District, Guangzhou 511458, China.
ORCID: 0000-0003-2349-3138

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Champignons › Levures › Candida › Candida albicans › Discovery of an Unexpected 1,4-Oxazepine-Linked
questionsmedicales.fr › Cellules › Cellules cultivées › Cellules cancéreuses en culture › Lignée cellulaire tumorale › Discovery of an Unexpected 1,4-Oxazepine-Linked
questionsmedicales.fr › Métabolisme › Dimérisation › Discovery of an Unexpected 1,4-Oxazepine-Linked
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Épigenèse génétique › Extinction de l'expression des gènes › Discovery of an Unexpected 1,4-Oxazepine-Linked
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Discovery of an Unexpected 1,4-Oxazepine-Linked
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Bâtonnets à Gram positif › Bâtonnets sporulés à Gram positif › Micromonosporaceae › Micromonospora › Discovery of an Unexpected 1,4-Oxazepine-Linked
questionsmedicales.fr › Phénomènes chimiques › Structure moléculaire › Discovery of an Unexpected 1,4-Oxazepine-Linked
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Azépines › Oxazépines › Discovery of an Unexpected 1,4-Oxazepine-Linked
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Oxidoreductases › Discovery of an Unexpected 1,4-Oxazepine-Linked
questionsmedicales.fr › Composés polycycliques › Composés macrocycliques › Polycétides › Discovery of an Unexpected 1,4-Oxazepine-Linked