Gestational Diabetes Mellitus: The Genetic Susceptibility Behind the Disease.
Journal
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme
ISSN: 1439-4286
Titre abrégé: Horm Metab Res
Pays: Germany
ID NLM: 0177722
Informations de publication
Date de publication:
Aug 2021
Aug 2021
Historique:
entrez:
12
8
2021
pubmed:
13
8
2021
medline:
11
1
2022
Statut:
ppublish
Résumé
Gestational diabetes mellitus (GDM), a type of pregnancy-specific glucose intolerance or hyperglycemia, is one of the most common metabolic disorders in pregnant women with 16.9% of the global prevalence of gestational hyperglycemia. Not only are women with GDM likely to develop T2DM, but their children are also at risk for birth complications or metabolic disease in adulthood. Therefore, identifying the potential risk factors for GDM is very important in the prevention and treatment of GDM. Previous studies have shown that genetic predisposition is an essential component in the occurrence of GDM. In this narrative review, we describe the role of polymorphisms in different functional genes associated with increased risk for GDM, and available evidence on genetic factors in the risk of GDM is summarized and discussed.
Substances chimiques
Glucose
IY9XDZ35W2
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
489-498Subventions
Organisme : 2018YFC1004300
ID : R & D Program of China
Organisme : 81670844
ID : National Natural Science Foundation Project of China
Organisme : QKH-JC-2019-1464
ID : Project of Guizhou Provincial Science and Technology Department
Organisme : QJH-KY-2017-077
ID : Excellent Talent Support Program of Guizhou Provincial Education Department
Organisme : QKH-PTRC-2017-5733-003
ID : Science and Technology Foundation of Guizhou Province
Organisme : QKH-PTRC-2018-5772-042
ID : Science and Technology Foundation of Guizhou Province
Organisme : 18-ZY-001
ID : Program for Excellent Young Talents of Zunyi Medical University
Organisme : ZSKH-HZ -2020-35
ID : the science and technology program project of Zunyi
Organisme : QJH-YJSCXJH-2019-094
ID : project of Scientific Research Foundation for Postgraduates of Guizhou Province
Informations de copyright
Thieme. All rights reserved.
Déclaration de conflit d'intérêts
The authors declare that they have no conflict of interest.