Daily energy expenditure through the human life course.


Journal

Science (New York, N.Y.)
ISSN: 1095-9203
Titre abrégé: Science
Pays: United States
ID NLM: 0404511

Informations de publication

Date de publication:
13 08 2021
Historique:
received: 27 08 2020
accepted: 21 06 2021
entrez: 13 8 2021
pubmed: 14 8 2021
medline: 21 8 2021
Statut: ppublish

Résumé

Total daily energy expenditure ("total expenditure") reflects daily energy needs and is a critical variable in human health and physiology, but its trajectory over the life course is poorly studied. We analyzed a large, diverse database of total expenditure measured by the doubly labeled water method for males and females aged 8 days to 95 years. Total expenditure increased with fat-free mass in a power-law manner, with four distinct life stages. Fat-free mass-adjusted expenditure accelerates rapidly in neonates to ~50% above adult values at ~1 year; declines slowly to adult levels by ~20 years; remains stable in adulthood (20 to 60 years), even during pregnancy; then declines in older adults. These changes shed light on human development and aging and should help shape nutrition and health strategies across the life span.

Identifiants

pubmed: 34385400
pii: 373/6556/808
doi: 10.1126/science.abe5017
pmc: PMC8370708
mid: NIHMS1718676
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

808-812

Subventions

Organisme : NIAMS NIH HHS
ID : U01 AR071160
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK085163
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK080763
Pays : United States
Organisme : NIA NIH HHS
ID : U01 AG020480
Pays : United States
Organisme : NIA NIH HHS
ID : U01 AG022132
Pays : United States
Organisme : NCRR NIH HHS
ID : S10 RR026764
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK072476
Pays : United States
Organisme : Intramural NIH HHS
ID : Z99 HD999999
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG029914
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA119171
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK080760
Pays : United States
Organisme : NIA NIH HHS
ID : R56 AG067200
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK030031
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK074387
Pays : United States
Organisme : NIDDK NIH HHS
ID : K23 DK068052
Pays : United States
Organisme : NIA NIH HHS
ID : U01 AG020478
Pays : United States
Organisme : Intramural NIH HHS
ID : ZIA HD000641
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK056781
Pays : United States

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

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Auteurs

Herman Pontzer (H)

Department of Evolutionary Anthropology, Duke University, Durham, NC, USA. herman.pontzer@duke.edu j.speakman@abdn.ac.uk yyamada831@gmail.com sagayama.hiroyuki.ka@u.tsukuba.ac.jp aluke@luc.edu jennifer.rood@pbrc.edu dschoell@nutrisci.wisc.edu k.westerterp@maastrichtuniversity.nl wwong@bcm.edu.
Duke Global Health Institute, Duke University, Durham, NC, USA.

Yosuke Yamada (Y)

Institute for Active Health, Kyoto University of Advanced Science, Kyoto, Japan. herman.pontzer@duke.edu j.speakman@abdn.ac.uk yyamada831@gmail.com sagayama.hiroyuki.ka@u.tsukuba.ac.jp aluke@luc.edu jennifer.rood@pbrc.edu dschoell@nutrisci.wisc.edu k.westerterp@maastrichtuniversity.nl wwong@bcm.edu.
National Institute of Health and Nutrition, National Institutes of Biomedical Innovation, Health and Nutrition, Tokyo, Japan.

Hiroyuki Sagayama (H)

Faculty of Health and Sport Sciences, University of Tsukuba, Ibaraki, Japan. herman.pontzer@duke.edu j.speakman@abdn.ac.uk yyamada831@gmail.com sagayama.hiroyuki.ka@u.tsukuba.ac.jp aluke@luc.edu jennifer.rood@pbrc.edu dschoell@nutrisci.wisc.edu k.westerterp@maastrichtuniversity.nl wwong@bcm.edu.

Philip N Ainslie (PN)

Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK.

Lene F Andersen (LF)

Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, 0317 Oslo, Norway.

Liam J Anderson (LJ)

Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK.
Crewe Alexandra Football Club, Crewe, UK.

Lenore Arab (L)

David Geffen School of Medicine, University of California, Los Angeles.

Issaad Baddou (I)

Unité Mixte de Recherche en Nutrition et Alimentation, CNESTEN-Université Ibn Tofail URAC39, Regional Designated Center of Nutrition Associated with AFRA/IAEA, Rabat, Morocco.

Kweku Bedu-Addo (K)

Department of Physiology, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Ellen E Blaak (EE)

Maastricht University, Maastricht, Netherlands.

Stephane Blanc (S)

Department of Nutritional Sciences, University of Wisconsin, Madison, WI, USA.
Institut Pluridisciplinaire Hubert Curien, CNRS Université de Strasbourg, UMR7178, France.

Alberto G Bonomi (AG)

Phillips Research, Eindoven, Netherlands.

Carlijn V C Bouten (CVC)

Maastricht University, Maastricht, Netherlands.

Pascal Bovet (P)

Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, Switzerland.

Maciej S Buchowski (MS)

Division of Gastroenterology, Hepatology, and Nutritiion, Department of Medicine, Vanderbilt University, Nashville, TN, USA.

Nancy F Butte (NF)

Department of Pediatrics, Baylor College of Medicine, USDA/ARS Children's Nutrition Research Center, Houston, TX, USA.

Stefan G Camps (SG)

Maastricht University, Maastricht, Netherlands.

Graeme L Close (GL)

Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK.

Jamie A Cooper (JA)

Department of Nutritional Sciences, University of Wisconsin, Madison, WI, USA.

Richard Cooper (R)

Department of Public Health Sciences, Parkinson School of Health Sciences and Public Health, Loyola University, Maywood, IL, USA.

Sai Krupa Das (SK)

Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA.

Lara R Dugas (LR)

Department of Public Health Sciences, Parkinson School of Health Sciences and Public Health, Loyola University, Maywood, IL, USA.

Ulf Ekelund (U)

Department of Sport Medicine, Norwegian School of Sport Sciences, Oslo, Norway.

Sonja Entringer (S)

Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Institute of Medical Psychology, Berlin, Germany.
School of Medicine, University of California Irvine, Irvine, CA, USA.

Terrence Forrester (T)

Solutions for Developing Countries, University of the West Indies, Mona, Kingston, Jamaica.

Barry W Fudge (BW)

Department of Biomedical and Life Sciences, University of Glasgow, Glasgow, UK.

Annelies H Goris (AH)

Maastricht University, Maastricht, Netherlands.

Michael Gurven (M)

Department of Anthropology, University of California Santa Barbara, Santa Barbara, CA, USA.

Catherine Hambly (C)

Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, UK.

Asmaa El Hamdouchi (A)

Unité Mixte de Recherche en Nutrition et Alimentation, CNESTEN-Université Ibn Tofail URAC39, Regional Designated Center of Nutrition Associated with AFRA/IAEA, Rabat, Morocco.

Marjije B Hoos (MB)

Maastricht University, Maastricht, Netherlands.

Sumei Hu (S)

State Key Laboratory of Molecular developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.

Noorjehan Joonas (N)

Central Health Laboratory, Ministry of Health and Wellness, Candos, Mauritius.

Annemiek M Joosen (AM)

Maastricht University, Maastricht, Netherlands.

Peter Katzmarzyk (P)

Pennington Biomedical Research Center, Baton Rouge, LA, USA.

Kitty P Kempen (KP)

Maastricht University, Maastricht, Netherlands.

Misaka Kimura (M)

Institute for Active Health, Kyoto University of Advanced Science, Kyoto, Japan.

William E Kraus (WE)

Department of Medicine, Duke University, Durham, NC, USA.

Robert F Kushner (RF)

Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

Estelle V Lambert (EV)

Health through Physical Activity, Lifestyle and Sport Research Centre (HPALS), Division of Exercise Science and Sports Medicine (ESSM), FIMS International Collaborating Centre of Sports Medicine, Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

William R Leonard (WR)

Department of Anthropology, Northwestern University, Evanston, IL, USA.

Nader Lessan (N)

Imperial College London Diabetes Centre, Abu Dhabi, United Arab Emirates and Imperial College London, London, UK.

Corby Martin (C)

Pennington Biomedical Research Center, Baton Rouge, LA, USA.

Anine C Medin (AC)

Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, 0317 Oslo, Norway.
Department of Nutrition and Public Health, Faculty of Health and Sport Sciences, University of Agder, 4630 Kristiansand, Norway.

Erwin P Meijer (EP)

Maastricht University, Maastricht, Netherlands.

James C Morehen (JC)

The FA Group, Burton-Upon-Trent, Staffordshire, UK.
Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK.

James P Morton (JP)

Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK.

Marian L Neuhouser (ML)

Division of Public Health Sciences, Fred Hutchinson Cancer Research Center and School of Public Health, University of Washington, Seattle, WA, USA.

Teresa A Nicklas (TA)

Department of Pediatrics, Baylor College of Medicine, USDA/ARS Children's Nutrition Research Center, Houston, TX, USA.

Robert M Ojiambo (RM)

Kenya School of Medicine, Moi University, Eldoret, Kenya.
Rwanda Division of Basic Sciences, University of Global Health Equity, Rwanda.

Kirsi H Pietiläinen (KH)

Helsinki University Central Hospital, Helsinki, Finland.

Yannis P Pitsiladis (YP)

School of Sport and Service Management, University of Brighton, Eastbourne, UK.

Jacob Plange-Rhule (J)

Department of Physiology, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Guy Plasqui (G)

Department of Nutrition and Movement Sciences, Maastricht University, Maastricht, Netherlands.

Ross L Prentice (RL)

Division of Public Health Sciences, Fred Hutchinson Cancer Research Center and School of Public Health, University of Washington, Seattle, WA, USA.

Roberto A Rabinovich (RA)

The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.

Susan B Racette (SB)

Program in Physical Therapy and Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.

David A Raichlen (DA)

Biological Sciences and Anthropology, University of Southern California, CA, USA.

Eric Ravussin (E)

Pennington Biomedical Research Center, Baton Rouge, LA, USA.

Rebecca M Reynolds (RM)

Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.

Susan B Roberts (SB)

Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA.

Albertine J Schuit (AJ)

School of Social and Behavioral Sciences, University of Tilburg, Tilburg, Netherlands.

Anders M Sjödin (AM)

Department of Nutrition, Exercise and Sports, Copenhagen University, Copenhagen, Denmark.

Eric Stice (E)

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford CA, USA.

Samuel S Urlacher (SS)

Department of Anthropology, Baylor University, Waco, TX, USA.

Giulio Valenti (G)

Maastricht University, Maastricht, Netherlands.
Phillips Research, Eindoven, Netherlands.

Ludo M Van Etten (LM)

Maastricht University, Maastricht, Netherlands.

Edgar A Van Mil (EA)

Maastricht University, Maastricht and Lifestyle Medicine Center for Children, Jeroen Bosch Hospital, Hertogenbosch, Netherlands.

Jonathan C K Wells (JCK)

Population, Policy, and Practice Research and Teaching Department, UCL Great Ormond Street Institute of Child Health, London, UK.

George Wilson (G)

Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK.

Brian M Wood (BM)

Department of Anthropology, University of California Los Angeles, Los Angeles, CA, USA.
Department of Human Behavior, Ecology, and Culture, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.

Jack Yanovski (J)

Growth and Obesity, Division of Intramural Research, NIH, Bethesda, MD, USA.

Tsukasa Yoshida (T)

National Institute of Health and Nutrition, National Institutes of Biomedical Innovation, Health and Nutrition, Tokyo, Japan.

Xueying Zhang (X)

Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, UK.
State Key Laboratory of Molecular developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.

Alexia J Murphy-Alford (AJ)

Nutritional and Health Related Environmental Studies Section, Division of Human Health, International Atomic Energy Agency, Vienna, Austria.

Cornelia Loechl (C)

Nutritional and Health Related Environmental Studies Section, Division of Human Health, International Atomic Energy Agency, Vienna, Austria.

Amy H Luke (AH)

Division of Epidemiology, Department of Public Health Sciences, Loyola University School of Medicine, Maywood, IL, USA. herman.pontzer@duke.edu j.speakman@abdn.ac.uk yyamada831@gmail.com sagayama.hiroyuki.ka@u.tsukuba.ac.jp aluke@luc.edu jennifer.rood@pbrc.edu dschoell@nutrisci.wisc.edu k.westerterp@maastrichtuniversity.nl wwong@bcm.edu.

Jennifer Rood (J)

Pennington Biomedical Research Center, Baton Rouge, LA, USA. herman.pontzer@duke.edu j.speakman@abdn.ac.uk yyamada831@gmail.com sagayama.hiroyuki.ka@u.tsukuba.ac.jp aluke@luc.edu jennifer.rood@pbrc.edu dschoell@nutrisci.wisc.edu k.westerterp@maastrichtuniversity.nl wwong@bcm.edu.

Dale A Schoeller (DA)

Biotech Center and Nutritional Sciences University of Wisconsin, Madison, WI, USA. herman.pontzer@duke.edu j.speakman@abdn.ac.uk yyamada831@gmail.com sagayama.hiroyuki.ka@u.tsukuba.ac.jp aluke@luc.edu jennifer.rood@pbrc.edu dschoell@nutrisci.wisc.edu k.westerterp@maastrichtuniversity.nl wwong@bcm.edu.

Klaas R Westerterp (KR)

Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University Medical Centre, Maastricht, Netherlands. herman.pontzer@duke.edu j.speakman@abdn.ac.uk yyamada831@gmail.com sagayama.hiroyuki.ka@u.tsukuba.ac.jp aluke@luc.edu jennifer.rood@pbrc.edu dschoell@nutrisci.wisc.edu k.westerterp@maastrichtuniversity.nl wwong@bcm.edu.

William W Wong (WW)

Department of Pediatrics, Baylor College of Medicine, USDA/ARS Children's Nutrition Research Center, Houston, TX, USA. herman.pontzer@duke.edu j.speakman@abdn.ac.uk yyamada831@gmail.com sagayama.hiroyuki.ka@u.tsukuba.ac.jp aluke@luc.edu jennifer.rood@pbrc.edu dschoell@nutrisci.wisc.edu k.westerterp@maastrichtuniversity.nl wwong@bcm.edu.

John R Speakman (JR)

Center for Energy Metabolism and Reproduction, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China. herman.pontzer@duke.edu j.speakman@abdn.ac.uk yyamada831@gmail.com sagayama.hiroyuki.ka@u.tsukuba.ac.jp aluke@luc.edu jennifer.rood@pbrc.edu dschoell@nutrisci.wisc.edu k.westerterp@maastrichtuniversity.nl wwong@bcm.edu.
Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, UK.
State Key Laboratory of Molecular developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
CAS Center of Excellence in Animal Evolution and Genetics, Kunming, China.

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