Current treatment concepts for osteochondral lesions of the talus.
Microfracture
Osteochondral lesion
Talus
Journal
Tzu chi medical journal
ISSN: 2223-8956
Titre abrégé: Tzu Chi Med J
Pays: India
ID NLM: 101770275
Informations de publication
Date de publication:
Historique:
received:
07
05
2020
revised:
29
05
2020
accepted:
13
06
2020
entrez:
13
8
2021
pubmed:
14
8
2021
medline:
14
8
2021
Statut:
epublish
Résumé
Osteochondral lesions of the talus (OLT) are a well-known cause of ankle joint pain and can sometimes lead to instability. These lesions are not only confined to articular hyaline cartilage, they can also affect the subchondral bone at the weight-bearing aspect of the talar dome. Nonoperative treatment is the preferred option for small lesions, however surgical intervention is recommended for large lesions or those for which conservative treatment has failed. Microfracture, abrasion arthroplasty and multiple drilling are all classified as bone marrow stimulation procedures; they are used to try to recruit precursor cells for cartilage regeneration and are especially suitable for small OLT lesions. For large lesions, osteochondral autografting and allografting are better options to reconstruct the articular defect, as they have better contours and mechanical strength. When there is limited subchondral bone involvement in large lesions, cell-based therapies such as autogenous chondrocyte implantation, potentially combined with a biomaterial matrix, are a promising option and acceptable functional outcomes have been reported. To provide evidence-based recommendations for clinicians, this article evaluates the currently available treatment strategies for OLT and their evolution over the past few decades.
Identifiants
pubmed: 34386361
doi: 10.4103/tcmj.tcmj_106_20
pii: TCMJ-33-243
pmc: PMC8323653
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
243-249Informations de copyright
Copyright: © 2020 Tzu Chi Medical Journal.
Déclaration de conflit d'intérêts
Dr. Chen-Chie Wang and Ing-Ho Chen, the editorial board members at Tzu Chi Medical Journal, had no role in the peer review process of or decision to publish this article. The other author declared no conflict of interest in writing this paper.
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