Juvenile Xanthogranuloma of the Pancreas in a Pediatric Patient Mimicking Pancreatic Neoplasm With High CA 19-9: Case Report and Literature Review.


Journal

Journal of pediatric hematology/oncology
ISSN: 1536-3678
Titre abrégé: J Pediatr Hematol Oncol
Pays: United States
ID NLM: 9505928

Informations de publication

Date de publication:
01 Apr 2022
Historique:
received: 19 03 2021
accepted: 09 06 2021
pubmed: 14 8 2021
medline: 20 4 2022
entrez: 13 8 2021
Statut: ppublish

Résumé

Juvenile xanthogranuloma (JXG) is a rare, non-Langerhans cell histiocytosis. It is usually a benign and self-limiting condition. The most common sites are skin and soft tissue. Pancreatic involvement is extremely rare. We present an unusual case of a 13-month-old female child with JXG of the pancreas and elevated cancer antigen 19-9. JXG should always be considered as a differential diagnosis for pediatric patients presenting with a pancreatic mass, solid and/or cystic in nature. Therefore, avoiding unnecessary invasive diagnostic procedures.

Identifiants

pubmed: 34387630
doi: 10.1097/MPH.0000000000002279
pii: 00043426-202204000-00037
doi:

Types de publication

Case Reports Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

e747-e750

Informations de copyright

Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

Références

Dehner LP. Juvenile xanthogranulomas in the first two decades of life: a clinicopathologic study of 174 cases with cutaneous and extracutaneous manifestations. Am J Surg Pathol. 2003;27:579–593.
Choi Y-H, Choi W, Han S, et al. A case of bilateral xanthogranulomatous pyelonephritis with renal failure. Korean J Nephrol. 2008;27:137–140.
Höck M, Zelger B, Schweigmannet G, et al. The various clinical spectra of juvenile xanthogranuloma: imaging for two case reports and review of the literature. BMC Pediatr. 2019;19:128.
Houston JP, Collins MC, Cameron I, et al. Xanthogranulomatous cholecystitis. Br J Surg. 1994;81:1030–1032.
Kwak J, Kim H-S, Joo M, et al. Combined xanthogranulomatous urachitis and bullous cystitis: a case report. Korean J Pathol. 2008;42:41–44.
Kim H-S, Joo M, Chang SH, et al. Xanthogranulomatous pancreatitis presents as a solid tumor mass: a case report. J Korean Med Sci. 2011;26:583.
Ikeura T, Takaoka M, Shimatani M, et al. Xanthogranulomatous inflammation of the peripancreatic region mimicking pancreatic cystic neoplasm. Intern Med. 2009;48:1881–1884.
Iso Y, Tagaya N, Kita J, et al. Xanthogranulomatous lesion of the pancreas mimicking pancreatic cancer. Med Sci Monit. 2008;14:CS130–CS133.
Iyer VK, Aggarwal S, Mathur M. Xanthogranulomatous pancreatitis: mass lesion of the pancreas simulating pancreatic carcinoma—a report of two cases. Indian J Pathol Microbiol. 2004;47:36–38.
Kamitani T, Nishimiya M, Takahashiet N, et al. Xanthogranulomatous pancreatitis associated with intraductal papillary mucinous tumor. AJR Am J Roentgenol. 2005;185:704–707.
Kang BW, Kim JW, Jo JC, et al. A case of xanthogranulomatous pancreatitis. Korean J Med. 2007;72 (suppl 2):S171–S174.
Kim YN, Park SY, Kimet YK, et al. Xanthogranulomatous pancreatitis combined with intraductal papillary mucinous carcinoma in situ. J Korean Med Sci. 2010;25:1814.
Okabayashi T, Nishimori I, Kobayashi M, et al. Xanthogranulomatous pancreatic abscess secondary to acute pancreatitis: two case reports. Hepatogastroenterology. 2007;54:1648–1651.
Shima Y, Saisaka Y, Furukita Y, et al. Resected xanthogranulomatous pancreatitis. J Hepatobiliary Pancreat Surg. 2008;15:240–242.
Ueno T, Hamanaka Y, Nishihara K, et al. Xanthogranulomatous change appearing in the pancreas cyst wall. Pancreas. 1993;8:649–651.
Uguz A, Yakan S, Gurcu B, et al. Xanthogranulomatous pancreatitis treated by duodenum-preserving pancreatic head resection. Hepatobiliary Pancreat Dis Int. 2010;9:216–218.
Heintz D, Megison S, Cope-Yokoyama S, et al. Pancreatic head tumor in an infant with new-onset jaundice. J Pediatr Gastroenterol Nutr. 2015;60:e14–e15.
Prasil P, Cayer S, Lemayet M, et al. Juvenile xanthogranuloma presenting as obstructive jaundice. J Pediatr Surg. 1999;34:1072–1073.
Atreyapurapu V, Keshwani A, Lingadakai R, et al. Xanthogranulomatous pancreatitis mimicking a malignant solid tumour. BMJ Case Rep. 2016;2016:bcr2015209934.
Freyer DR, Kennedy R, Bostromet BC, et al. Juvenile xanthogranuloma: forms of systemic disease and their clinical implications. J Pediatr. 1996;129:227–237.
Maintz L, Wenzel J, Irnichet M, et al. Successful treatment of systemic juvenile xanthogranulomatosis with cytarabine and 2-chlorodeoxyadenosine: case report and review of the literature. Br J Dermatol. 2017;176:481–487.

Auteurs

Eman Al-Antary (E)

Pediatric Hematology/Oncology and Bone Marrow Transplantation Program.

Avanti Gupte (A)

Pediatric Hematology/Oncology and Bone Marrow Transplantation Program.

Janet Poulik (J)

Pediatric Pathology Department.

Justin Klein (J)

Pediatric General Surgery Program, Children's Hospital of Michigan, Central Michigan University and Wayne State University School of Medicine, Detroit, MI.

Hamza S Gorsi (HS)

Pediatric Hematology/Oncology and Bone Marrow Transplantation Program.

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