Platycodon grandiflorus polysaccharides inhibit Pseudorabies virus replication via downregulating virus-induced autophagy.

Animals Autophagy Cell Line Herpesvirus 1, Suid Platycodon Polysaccharides Pseudorabies Virus Replication
Akt/mTOR Autophagy Platycodon grandiflorus polysaccharide Pseudorabies virus Replication

Journal

Research in veterinary science
ISSN: 1532-2661
Titre abrégé: Res Vet Sci
Pays: England
ID NLM: 0401300

Informations de publication

Date de publication:
Nov 2021
Historique:
received: 19 04 2021
revised: 26 06 2021
accepted: 05 08 2021
pubmed: 15 8 2021
medline: 16 10 2021
entrez: 14 8 2021
Statut: ppublish

Résumé

Pseudorabies virus (PRV) is one of the common pathogens in farms. Platycodon grandiflorus polysaccharide (PGPS) has been reported with a variety of biological activities. Autophagy is one of the vital mechanisms for cells to cope with virus infection, and it may also inhibit or promote virus replication. This study was conducted to investigate the antiviral activity of total PGPS(PGPS

Identifiants

DOI: 10.1016/j.rvsc.2021.08.004 PMID: 34391058
pubmed: 34391058
pii: S0034-5288(21)00256-3
doi: 10.1016/j.rvsc.2021.08.004
pii:
doi:

Substances chimiques

Polysaccharides 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

18-25

Informations de copyright

Copyright © 2021. Published by Elsevier Ltd.

Auteurs

Yuxiao Xing (Y)

College of Veterinary Medicine, Shandong Agricultural University, Tai'an, Shandong 271018, China.

Lumei Wang (L)

College of Veterinary Medicine, Shandong Agricultural University, Tai'an, Shandong 271018, China.

Guanlong Xu (G)

China Institute of Veterinary Drug Control, Beijing 100081, China.

Shuhua Guo (S)

College of Veterinary Medicine, Shandong Agricultural University, Tai'an, Shandong 271018, China.

Meihua Zhang (M)

College of Veterinary Medicine, Shandong Agricultural University, Tai'an, Shandong 271018, China.

Guodong Cheng (G)

College of Veterinary Medicine, Shandong Agricultural University, Tai'an, Shandong 271018, China.

Yongxia Liu (Y)

Research Center for Animal Disease Control Engineering, Shandong Agricultural University, Tai'an, Shandong 271018, China. Electronic address: liuyongxia@sdau.edu.cn.

Jianzhu Liu (J)

College of Veterinary Medicine, Shandong Agricultural University, Tai'an, Shandong 271018, China. Electronic address: liujz@sdau.edu.cn.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Platycodon grandiflorus polysaccharides...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Autophagie › Platycodon grandiflorus polysaccharides...
questionsmedicales.fr › Cellules › Cellules cultivées › Lignée cellulaire › Platycodon grandiflorus polysaccharides...
questionsmedicales.fr › Virus › Virus à ADN › Herpesviridae › Alphaherpesvirinae › Varicellovirus › Herpèsvirus porcin de type 1 › Platycodon grandiflorus polysaccharides...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Campanulaceae › Platycodon › Platycodon grandiflorus polysaccharides...
questionsmedicales.fr › Glucides › Polyosides › Platycodon grandiflorus polysaccharides...
questionsmedicales.fr › Maladies de l'animal › Maladie d'Aujeszky › Platycodon grandiflorus polysaccharides...
questionsmedicales.fr › Phénomènes microbiologiques › Phénomènes physiologiques viraux › Réplication virale › Platycodon grandiflorus polysaccharides...