Waitlist Mortality and Posttransplant Outcomes in African Americans with Autoimmune Liver Diseases.
Journal
Journal of transplantation
ISSN: 2090-0007
Titre abrégé: J Transplant
Pays: United States
ID NLM: 101519118
Informations de publication
Date de publication:
2021
2021
Historique:
received:
22
10
2020
revised:
11
02
2021
accepted:
25
07
2021
entrez:
16
8
2021
pubmed:
17
8
2021
medline:
17
8
2021
Statut:
epublish
Résumé
Liver transplantation is indicated in end-stage liver disease due to autoimmune diseases. The liver allocation system can be affected by disparities such as decreased liver transplant referrals for racial minorities, especially African Americans that negatively impact the pre- and posttransplant outcomes. To determine differences in waitlist survival and posttransplant graft survival rates between African American and Caucasian patients with autoimmune liver diseases. African Americans were more likely to be removed from the waitlist for death or clinical deterioration (subdistribution hazard ratio (SHR) 1.26, 95% CI 1-1.58, Despite the current efforts to reduce racial disparities, we found that African Americans are more likely to die on the waitlist for liver transplant and are less likely to be transplanted, with no differences in graft survival rates. The persistence of healthcare disparities continues to negatively impact African Americans.
Sections du résumé
BACKGROUND
BACKGROUND
Liver transplantation is indicated in end-stage liver disease due to autoimmune diseases. The liver allocation system can be affected by disparities such as decreased liver transplant referrals for racial minorities, especially African Americans that negatively impact the pre- and posttransplant outcomes.
AIM
OBJECTIVE
To determine differences in waitlist survival and posttransplant graft survival rates between African American and Caucasian patients with autoimmune liver diseases.
RESULTS
RESULTS
African Americans were more likely to be removed from the waitlist for death or clinical deterioration (subdistribution hazard ratio (SHR) 1.26, 95% CI 1-1.58,
CONCLUSIONS
CONCLUSIONS
Despite the current efforts to reduce racial disparities, we found that African Americans are more likely to die on the waitlist for liver transplant and are less likely to be transplanted, with no differences in graft survival rates. The persistence of healthcare disparities continues to negatively impact African Americans.
Identifiants
pubmed: 34394979
doi: 10.1155/2021/6692049
pmc: PMC8357471
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
6692049Informations de copyright
Copyright © 2021 John Paul Nsubuga et al.
Déclaration de conflit d'intérêts
The authors have no conflicts of interest or sources of funding to declare.
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