Potency of spirulina (
Inorganic
arsenic
lipid peroxidation
rats
spirulina
total protein
Journal
Journal of advanced veterinary and animal research
ISSN: 2311-7710
Titre abrégé: J Adv Vet Anim Res
Pays: Bangladesh
ID NLM: 101647585
Informations de publication
Date de publication:
Jun 2021
Jun 2021
Historique:
received:
10
02
2021
revised:
28
04
2021
accepted:
19
05
2021
entrez:
16
8
2021
pubmed:
17
8
2021
medline:
17
8
2021
Statut:
epublish
Résumé
Natural substances found in dietary sources and medicinal plants have attracted considerable attention in recent years as chemopreventive agents. Spirulina is a blue-green alga that possesses chemopreventive properties. The purpose of this study was to determine the effect of spirulina on rats with inorganic arsenic (As) [sodium arsenite (NaAsO 120 rats were randomly assigned to 10 groups and designated T0, T1, T2, T3, T4, T5, T6, T7, T8, and T9. One group was kept as a control (T0) that received no treatment. The seven groups received 3.0 mg of NaAsO The efficacy of both spirulina in preventing lipid peroxidation caused by As was determined quantitatively by measuring the rats' serum malondialdehyde (MDA). The results indicated that As supplementation increased serum MDA levels, whereas both types of spirulina significantly decreased them. The highest dose of Ab-Sp (2.0 gm/kg feed) was found to be the most effective in preventing lipid peroxidation in rats treated with inorganic As. Ab-Sp could be a natural, cost-effective, and safe measure to mitigate As toxicity.
Identifiants
pubmed: 34395605
doi: 10.5455/javar.2021.h519
pmc: PMC8280986
doi:
Types de publication
Journal Article
Langues
eng
Pagination
330-338Informations de copyright
Copyright: © Journal of Advanced Veterinary and Animal Research.
Déclaration de conflit d'intérêts
The authors declare that no conflict of interests exists.
Références
Antioxidants (Basel). 2019 Mar 25;8(3):
pubmed: 30934586
Cancers (Basel). 2010 Apr 08;2(2):376-96
pubmed: 24281075
Chemosphere. 2017 Jan;167:454-461
pubmed: 27750169
Acta Pharmacol Sin. 2001 Dec;22(12):1121-4
pubmed: 11749812
Toxicol Sci. 2009 Feb;107(2):312-23
pubmed: 19015167
Mol Cell Biochem. 2001 Oct;226(1-2):27-38
pubmed: 11768236
Int J Environ Res Public Health. 2005 Dec;2(3-4):385-93
pubmed: 16819093
Int J Biomed Sci. 2014 Mar;10(1):52-60
pubmed: 24711750
Anal Biochem. 1979 Jun;95(2):351-8
pubmed: 36810
J Environ Pathol Toxicol Oncol. 2020;39(2):149-157
pubmed: 32749124
Arch Toxicol. 2014 May;88(5):1043-67
pubmed: 24691704
Regul Toxicol Pharmacol. 2020 Feb;110:104539
pubmed: 31765675
Environ Int. 2019 Jun;127:819-847
pubmed: 31051325
JAMA. 2008 Aug 20;300(7):814-22
pubmed: 18714061
J Sci Food Agric. 2017 Feb;97(3):724-732
pubmed: 27507218
Environ Int. 2021 Apr;149:106401
pubmed: 33549917
Nutr Res Pract. 2008 Winter;2(4):295-300
pubmed: 20016733
AIMS Genet. 2017 Apr 18;4(2):103-137
pubmed: 31435505
Oxid Med Cell Longev. 2016;2016:7174351
pubmed: 26881036
Environ Pollut. 2021 Feb 15;271:116333
pubmed: 33535364
Biomolecules. 2020 Feb 05;10(2):
pubmed: 32033297
Molecules. 2020 Nov 06;25(21):
pubmed: 33171936