COVID-19 infection in patients with sarcoidosis: susceptibility and clinical outcomes.


Journal

Current opinion in pulmonary medicine
ISSN: 1531-6971
Titre abrégé: Curr Opin Pulm Med
Pays: United States
ID NLM: 9503765

Informations de publication

Date de publication:
01 09 2021
Historique:
entrez: 16 8 2021
pubmed: 17 8 2021
medline: 9 10 2021
Statut: ppublish

Résumé

Patients with sarcoidosis may be at higher risk of coronavirus disease-19 (COVID-19) as over 90% of the patients have pulmonary involvement and many are treated with immunosuppressive agents. This review will summarize the current literature regarding sarcoidosis and COVID-19, with a particular focus on susceptibility, clinical outcomes, management, and approach to vaccination. Data about COVID-19 and sarcoidosis include a number of case series and reports, cohort studies, and registries. Literature is not conclusive whether patients with sarcoidosis have increased susceptibility to COVID-19. Patients with moderate to severe impaired pulmonary function may be at increased risk of adverse outcomes and mortality. Whether immunosuppressive medication increases risk of COVID-19 severity or affects vaccination response is not yet clear. Novel approaches, such as telemedicine and home monitoring programs, are promising to ensure continuity of care for patients with sarcoidosis during the COVID-19 pandemic. Current evidence about the risk and clinical outcomes of COVID-19 infection in patient with sarcoidosis, is mainly extrapolated from other immune-mediated diseases. Hence, further research that focuses on the sarcoidosis population is warranted.

Identifiants

pubmed: 34397613
doi: 10.1097/MCP.0000000000000812
pii: 00063198-202109000-00025
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

463-471

Informations de copyright

Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

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Auteurs

Vivienne Kahlmann (V)

Centre of Excellence for Interstitial Lung Diseases and Sarcoidosis, Department of Respiratory Medicine, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.

Michael Manansala (M)

Department of Medicine, Academic Internal Medicine.

Catharina C Moor (CC)

Centre of Excellence for Interstitial Lung Diseases and Sarcoidosis, Department of Respiratory Medicine, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.

Shiva Shahrara (S)

Division of Rheumatology, Department of Medicine, University of Illinois at Chicago.
Jesse Brown VA Medical Center, Chicago, Illinois, USA.

Marlies S Wijsenbeek (MS)

Centre of Excellence for Interstitial Lung Diseases and Sarcoidosis, Department of Respiratory Medicine, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.

Nadera J Sweiss (NJ)

Division of Rheumatology, Department of Medicine, University of Illinois at Chicago.

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