Prevalence of obesity and diabetes in older people with sarcopenia defined according to EWGSOP2 and FNHI criteria.
Acute care
Diabetes
Mortality
Sarcopenia
Sarcopenic obesity
Journal
Aging clinical and experimental research
ISSN: 1720-8319
Titre abrégé: Aging Clin Exp Res
Pays: Germany
ID NLM: 101132995
Informations de publication
Date de publication:
Jan 2022
Jan 2022
Historique:
received:
30
04
2021
accepted:
30
07
2021
pubmed:
17
8
2021
medline:
1
2
2022
entrez:
16
8
2021
Statut:
ppublish
Résumé
Although the prevalence of sarcopenic obesity is increasing, nowadays a universally accepted definition still does not exist. Because, this clinical entity is defined as the combination of obesity and sarcopenia, the diagnosis appears to be strictly linked to criteria used for sarcopenia and the available prevalence data are not uniform. To investigate the prevalence of sarcopenic obesity in older persons according to EWGSOP2 and FNIH criteria. Second, to evaluate the prevalence of diabetes in patients with sarcopenia diagnosed by the two definitions. Observational multicenter study performed in 2014 on older patients admitted to 12 Italian hospitals (GLISTEN Study). Data were collected through standardized questionnaires, which assessed: socio-demographic data, cognitive status, functional abilities, pharmacological therapy, comorbidities, and blood tests. Moreover, muscle mass and strength and physical performance were evaluated. Six hundred and ten were included in the analyses. Among sarcopenic patients, the prevalence of sarcopenic obesity was 30.8% with FNIH and 0% with EWGSOP2 criteria. According to EWGSOP2 criteria, 23.7% of sarcopenic and 30.8% of non-sarcopenic patients were affected by diabetes (p = 0.101); otherwise, using FNIH criteria, 36.3% of sarcopenic and 26.9% of non-sarcopenic patients were diabetic (p = 0.030). After adjustment for potential confounders, diabetic patients had a 73% higher probability of being sarcopenic according to FNIH criteria (OR 1.73; 95% CI 1.13-2.64). The EWGSOP2 and FNIH sarcopenia criteria are differently related to the prevalence of obesity and diabetes. The EWGSOP2 criteria seem to be not suitable to identify people with sarcopenic obesity.
Sections du résumé
BACKGROUND
BACKGROUND
Although the prevalence of sarcopenic obesity is increasing, nowadays a universally accepted definition still does not exist. Because, this clinical entity is defined as the combination of obesity and sarcopenia, the diagnosis appears to be strictly linked to criteria used for sarcopenia and the available prevalence data are not uniform. To investigate the prevalence of sarcopenic obesity in older persons according to EWGSOP2 and FNIH criteria. Second, to evaluate the prevalence of diabetes in patients with sarcopenia diagnosed by the two definitions.
METHODS
METHODS
Observational multicenter study performed in 2014 on older patients admitted to 12 Italian hospitals (GLISTEN Study). Data were collected through standardized questionnaires, which assessed: socio-demographic data, cognitive status, functional abilities, pharmacological therapy, comorbidities, and blood tests. Moreover, muscle mass and strength and physical performance were evaluated.
RESULTS
RESULTS
Six hundred and ten were included in the analyses. Among sarcopenic patients, the prevalence of sarcopenic obesity was 30.8% with FNIH and 0% with EWGSOP2 criteria. According to EWGSOP2 criteria, 23.7% of sarcopenic and 30.8% of non-sarcopenic patients were affected by diabetes (p = 0.101); otherwise, using FNIH criteria, 36.3% of sarcopenic and 26.9% of non-sarcopenic patients were diabetic (p = 0.030). After adjustment for potential confounders, diabetic patients had a 73% higher probability of being sarcopenic according to FNIH criteria (OR 1.73; 95% CI 1.13-2.64).
CONCLUSIONS
CONCLUSIONS
The EWGSOP2 and FNIH sarcopenia criteria are differently related to the prevalence of obesity and diabetes. The EWGSOP2 criteria seem to be not suitable to identify people with sarcopenic obesity.
Identifiants
pubmed: 34398439
doi: 10.1007/s40520-021-01949-1
pii: 10.1007/s40520-021-01949-1
pmc: PMC8795057
doi:
Types de publication
Journal Article
Multicenter Study
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
113-120Investigateurs
Gloria Brombo
(G)
Beatrice Ortolani
(B)
Elisabetta Savino
(E)
Elisa Maietti
(E)
Alberto Fisichella
(A)
Valeria Buttò
(V)
Mauro Zamboni
(M)
Cesare Caliari
(C)
Elena Ferrari
(E)
Francesco Orso
(F)
Flavia Sacco
(F)
Maria Laura Di Meo
(ML)
Anna Paola Cerri
(AP)
Marco Motta
(M)
Francesca Pittella
(F)
Alessandra Bonfanti
(A)
Sergio Fusco
(S)
Roberto Schepisi
(R)
Christian Ferro
(C)
Antonino Catalano
(A)
Stefano Caruso
(S)
Luca Soraci
(L)
Lorenzo Marchese
(L)
Luca Agosta
(L)
Claudia Basile
(C)
Carla Coppola
(C)
Anna Maria Dalise
(AM)
Ilaria Fava
(I)
Olga Catte
(O)
Maura Orru'
(M)
Paolo Salaris
(P)
Anna Maria Martone
(AM)
Elena Ortolani
(E)
Sara Salini
(S)
Giuseppina dell'Aquila
(G)
Barbara Carrieri
(B)
Informations de copyright
© 2021. The Author(s).
Références
J Gerontol A Biol Sci Med Sci. 2014 Jul;69(7):871-7
pubmed: 24325896
Aging Clin Exp Res. 2020 Sep;32(9):1675-1687
pubmed: 31625078
J Gerontol A Biol Sci Med Sci. 2014 May;69(5):567-75
pubmed: 24737559
Eur Geriatr Med. 2020 Oct;11(5):725-736
pubmed: 32504420
Diabetes Metab Syndr Obes. 2014 Dec 04;7:587-91
pubmed: 25506234
J Gerontol A Biol Sci Med Sci. 2014 May;69(5):547-58
pubmed: 24737557
Int J Obes (Lond). 2021 Mar;45(3):650-658
pubmed: 33414486
World J Diabetes. 2019 May 15;10(5):311-323
pubmed: 31139318
Osteoporos Int. 2009 Nov;20(11):1807-20
pubmed: 19543765
Diabetes Care. 2012 Aug;35(8):1672-9
pubmed: 22596176
Acta Diabetol. 2016 Dec;53(6):879-889
pubmed: 27393005
Phys Ther. 2011 Jun;91(6):923-30
pubmed: 21474636
Eur Geriatr Med. 2020 Oct;11(5):713-714
pubmed: 32514749
JAMA. 1997 Mar 5;277(9):728-34
pubmed: 9042845
Aging Clin Exp Res. 2021 Feb;33(2):247-252
pubmed: 31845200
Int J Obes (Lond). 2020 Oct;44(10):2092-2100
pubmed: 32518354
Clin Nutr. 2020 Aug;39(8):2368-2388
pubmed: 31813698
J Gerontol A Biol Sci Med Sci. 2014 May;69(5):559-66
pubmed: 24737558
J Clin Epidemiol. 1992 Jun;45(6):613-9
pubmed: 1607900
Diabetes Care. 2007 Jun;30(6):1507-12
pubmed: 17363749
Eur Geriatr Med. 2020 Apr;11(2):239-246
pubmed: 32297186
J Am Geriatr Soc. 2013 Jun;61(6):974-80
pubmed: 23647372
Nat Rev Endocrinol. 2018 Sep;14(9):513-537
pubmed: 30065268
Age Ageing. 2019 Jan 1;48(1):16-31
pubmed: 30312372
Diabetes Care. 2010 Jul;33(7):1497-9
pubmed: 20413515
J Gerontol A Biol Sci Med Sci. 2017 Oct 12;72(11):1575-1581
pubmed: 28329345
Int J Obes (Lond). 2021 Jan;45(1):170-183
pubmed: 33037328
PLoS One. 2014 Dec 04;9(12):e113637
pubmed: 25474696
Exp Gerontol. 2020 Feb;130:110798
pubmed: 31816424
J Nutr. 1997 May;127(5 Suppl):990S-991S
pubmed: 9164280
Calcif Tissue Int. 2014 Apr;94(4):363-72
pubmed: 24390582
J Gerontol A Biol Sci Med Sci. 2020 Jun 18;75(7):1331-1337
pubmed: 31628464