Host-Microbe Metagenomics: a Lens To Refocus Our Perspective on Infectious and Inflammatory Diseases.
Journal
mSystems
ISSN: 2379-5077
Titre abrégé: mSystems
Pays: United States
ID NLM: 101680636
Informations de publication
Date de publication:
31 Aug 2021
31 Aug 2021
Historique:
pubmed:
18
8
2021
medline:
18
8
2021
entrez:
17
8
2021
Statut:
ppublish
Résumé
A dynamic relationship involving pathogen, host immune response, and microbiome characterizes the biological framework of many infectious and inflammatory diseases. Combined host/microbe metagenomics (mNGS) enables simultaneous assessment of all three features, enabling the study and diagnosis of diverse infectious and inflammatory processes ranging from pneumonia to sepsis to inflammatory diseases such as rheumatoid arthritis. Host/microbe mNGS holds promise for new mechanistic insights, diagnostic approaches, and precision medicine interventions.
Identifiants
pubmed: 34402649
doi: 10.1128/mSystems.00404-21
pmc: PMC8409739
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e0040421Subventions
Organisme : NHLBI NIH HHS
ID : K23 HL138461
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL155418
Pays : United States
Organisme : HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI)
ID : R01HL155418-01
Organisme : HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI)
ID : 1K23HL138461-01A1
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