High estradiol and low testosterone levels are associated with critical illness in male but not in female COVID-19 patients: a retrospective cohort study.

Aged Aged, 80 and over COVID-19 / blood Critical Care Critical Illness Estradiol / blood Extracorporeal Membrane Oxygenation Female Humans Hypogonadism / pathology Intensive Care Units Interferon-gamma / blood Male Middle Aged Retrospective Studies Risk Factors SARS-CoV-2 Severity of Illness Index Sex Distribution Testosterone / blood

COVID-19 SARS-CoV-2 critical illness cytokines sex differences sex hormones

Journal

Emerging microbes & infections

ISSN: 2222-1751

Titre abrégé: Emerg Microbes Infect

Pays: United States

ID NLM: 101594885

Informations de publication

Date de publication:
Dec 2021

Historique:

pubmed: 18 8 2021

medline: 24 9 2021

entrez: 17 8 2021

Statut: ppublish

Résumé

Male sex was repeatedly identified as a risk factor for death and intensive care admission. However, it is yet unclear whether sex hormones are associated with disease severity in COVID-19 patients. In this study, we analysed sex hormone levels (estradiol and testosterone) of male and female COVID-19 patients (

Identifiants

DOI: 10.1080/22221751.2021.1969869 PMID: 34402750 PMC: PMC8451658

pubmed: 34402750

doi: 10.1080/22221751.2021.1969869

pmc: PMC8451658

doi:

Substances chimiques

IFNG protein, human 0

Testosterone 3XMK78S47O

Estradiol 4TI98Z838E

Interferon-gamma 82115-62-6

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

Pagination

1807-1818

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