Successful lung transplantation with graft recovered after thoracoabdominal normothermic perfusion from donor after circulatory death.
clinical research/practice
donors and donation: donation after circulatory death (DCD)
lung (allograft) function/dysfunction
lung transplantation/pulmonology
organ acceptance
organ perfusion and preservation
organ procurement
organ procurement and allocation
Journal
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
ISSN: 1600-6143
Titre abrégé: Am J Transplant
Pays: United States
ID NLM: 100968638
Informations de publication
Date de publication:
01 2022
01 2022
Historique:
revised:
14
07
2021
received:
06
06
2021
accepted:
30
07
2021
pubmed:
18
8
2021
medline:
1
2
2022
entrez:
17
8
2021
Statut:
ppublish
Résumé
Lung transplantation with lungs procured from donors after circulatory death (DCD) has been established as an alternative technique to traditional donation after brain death (DBD) with comparable outcomes. Recently, in situ thoracoabdominal normothermic regional perfusion (TA-NRP) has emerged as a novel technique employed in the procurement of cardiac allografts after circulatory death. TA-NRP, in contrast to ex situ machine perfusion, has the advantage of allowing in situ assessment of donor organs prior to final acceptance. However, there are some concerns that this technique may adversely impact the quality of lung allografts. Here, we present a case of a successful bilateral sequential lung transplantation in a patient with postinflammatory pulmonary fibrosis due to acute respiratory distress syndrome (ARDS), with lungs procured after normothermic in situ lung perfusion. Apart from the lungs, heart, liver, and kidneys were also successfully transplanted from this donor.
Identifiants
pubmed: 34403207
doi: 10.1111/ajt.16806
pii: S1600-6135(22)08064-9
doi:
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
294-298Informations de copyright
© 2021 The American Society of Transplantation and the American Society of Transplant Surgeons.
Références
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