Knowledge, attitude and practices towards visceral leishmaniasis among HIV patients: A cross-sectional study from Bihar, India.
Journal
PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081
Informations de publication
Date de publication:
2021
2021
Historique:
received:
12
04
2021
accepted:
02
08
2021
entrez:
17
8
2021
pubmed:
18
8
2021
medline:
15
12
2021
Statut:
epublish
Résumé
In the Indian state of Bihar, visceral leishmaniasis (VL) is a major public health issue that has been aggravated by the rising incidence of new Human immunodeficiency virus (HIV) infections. In endemic areas, the risk of VL infections in patients living with HIV (PLHIV) is higher. It is important to investigate the disease-related knowledge, attitude, and practices (KAP) of PLHIV in Bihar in order to monitor HIV/VL co-infection. Adequate knowledge, a positive attitude, and good practices for VL control are essential to stamp out the disease. This study investigated the KAP towards VL in HIV patients attending antiretroviral therapy (ART) clinic at ICMR-RMRIMS, Patna. A questionnaire based cross-sectional study was performed among 120 HIV patients aged ≥18 years, to evaluate their KAP regarding visceral leishmaniasis. For the KAP indicators, each correct answer received a score of 1, while unsure and incorrect responses received a score of 0. Descriptive statistics and logistic regression were used for the analysis. Data analysis was performed using Statistical Package for the Social Sciences (SPSS) version 27. The study population had a male (68.30%) preponderance with a mean age of 37.03 years ± 9.80 years of standard deviation. The majority (93.30%) of the study participants had previously heard about VL. Only 32.10% of those who had heard about VL knew that the disease was transmitted by the sandfly. Most (80.40%) of the study respondents were ignorant of the sandfly breeding grounds. The vast majority (75.90%) had no idea how to recognize sandflies and were unaware of their biting time, leishmaniasis transmission season, and preventive practices. Although PLHIV are vulnerable to VL, only 27.70% of them agreed that VL is a fatal disease if untreated, and 42.90% believed they wear not at risk of developing the disease. Regarding the control methods of sandflies, 28.60% of participants did not use any methods to avoid sandfly bites. The multivariable analysis revealed that occupation and family history were the two independent predictor variables of the knowledge index. Age and gender were significantly associated with attitude towards VL. Participants working as laborers had significantly lesser odds (AOR: 0.248, 95% CI: 0.073-0.844) to follow good preventive practices. There were significantly higher odds of having good practice among participants aged 18-40 years (AOR: 6.866, 95% CI: 1.694-27.834) and those residing in urban areas (AOR: 4.159, 95% CI: 1.317-13.139) than their peers. Overall, 27.7% of respondents were knowledgeable, 41.1% had a positive mindset, and 33.9% had strong VL preventive habits, according to the study. The study determined a remarkable gap in the knowledge attitude and practices towards VL among PLHIV. This underscores the need of augmented health education initiatives for PLHIV in endemic areas for good VL awareness and preventive practices.
Sections du résumé
BACKGROUND
In the Indian state of Bihar, visceral leishmaniasis (VL) is a major public health issue that has been aggravated by the rising incidence of new Human immunodeficiency virus (HIV) infections. In endemic areas, the risk of VL infections in patients living with HIV (PLHIV) is higher. It is important to investigate the disease-related knowledge, attitude, and practices (KAP) of PLHIV in Bihar in order to monitor HIV/VL co-infection. Adequate knowledge, a positive attitude, and good practices for VL control are essential to stamp out the disease. This study investigated the KAP towards VL in HIV patients attending antiretroviral therapy (ART) clinic at ICMR-RMRIMS, Patna.
METHODS
A questionnaire based cross-sectional study was performed among 120 HIV patients aged ≥18 years, to evaluate their KAP regarding visceral leishmaniasis. For the KAP indicators, each correct answer received a score of 1, while unsure and incorrect responses received a score of 0. Descriptive statistics and logistic regression were used for the analysis. Data analysis was performed using Statistical Package for the Social Sciences (SPSS) version 27.
RESULTS
The study population had a male (68.30%) preponderance with a mean age of 37.03 years ± 9.80 years of standard deviation. The majority (93.30%) of the study participants had previously heard about VL. Only 32.10% of those who had heard about VL knew that the disease was transmitted by the sandfly. Most (80.40%) of the study respondents were ignorant of the sandfly breeding grounds. The vast majority (75.90%) had no idea how to recognize sandflies and were unaware of their biting time, leishmaniasis transmission season, and preventive practices. Although PLHIV are vulnerable to VL, only 27.70% of them agreed that VL is a fatal disease if untreated, and 42.90% believed they wear not at risk of developing the disease. Regarding the control methods of sandflies, 28.60% of participants did not use any methods to avoid sandfly bites. The multivariable analysis revealed that occupation and family history were the two independent predictor variables of the knowledge index. Age and gender were significantly associated with attitude towards VL. Participants working as laborers had significantly lesser odds (AOR: 0.248, 95% CI: 0.073-0.844) to follow good preventive practices. There were significantly higher odds of having good practice among participants aged 18-40 years (AOR: 6.866, 95% CI: 1.694-27.834) and those residing in urban areas (AOR: 4.159, 95% CI: 1.317-13.139) than their peers. Overall, 27.7% of respondents were knowledgeable, 41.1% had a positive mindset, and 33.9% had strong VL preventive habits, according to the study.
CONCLUSION
The study determined a remarkable gap in the knowledge attitude and practices towards VL among PLHIV. This underscores the need of augmented health education initiatives for PLHIV in endemic areas for good VL awareness and preventive practices.
Identifiants
pubmed: 34404087
doi: 10.1371/journal.pone.0256239
pii: PONE-D-21-12031
pmc: PMC8370793
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0256239Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
Asian Pac J Trop Biomed. 2014 Jul;4(7):566-9
pubmed: 25183278
PLoS Negl Trop Dis. 2014 Apr 17;8(4):e2799
pubmed: 24743328
Clin Infect Dis. 2014 Aug 15;59(4):552-5
pubmed: 24814660
Am J Trop Med Hyg. 2006 Sep;75(3):505-8
pubmed: 16968930
Sci Rep. 2017 Oct 17;7(1):13325
pubmed: 29042642
Southeast Asian J Trop Med Public Health. 2010 Jan;41(1):1-12
pubmed: 20578475
PLoS Negl Trop Dis. 2018 May 10;12(5):e0006375
pubmed: 29746470
Trop Med Health. 2017 May 12;45:13
pubmed: 28515660
Front Immunol. 2018 Jan 12;8:1943
pubmed: 29375567
Ann Trop Med Parasitol. 2003 Oct;97 Suppl 1:29-45
pubmed: 14678631
Curr Opin Infect Dis. 2013 Feb;26(1):1-9
pubmed: 23221770
PLoS One. 2015 Jun 19;10(6):e0130929
pubmed: 26090870
Ther Adv Infect Dis. 2016 Jun;3(3-4):98-109
pubmed: 27536354
Am J Trop Med Hyg. 2018 Mar;98(3):857-863
pubmed: 29280426
Clin Microbiol Rev. 2008 Apr;21(2):334-59, table of contents
pubmed: 18400800
BMJ. 2019 Jan 22;364:k5224
pubmed: 30670453
Heliyon. 2020 Jan 06;6(1):e03152
pubmed: 32042949
Health Qual Life Outcomes. 2017 Aug 30;15(1):65
pubmed: 28851361
PLoS Negl Trop Dis. 2020 May 4;14(5):e0008254
pubmed: 32365060
BMC Infect Dis. 2021 Mar 17;21(1):269
pubmed: 33731042
PLoS Negl Trop Dis. 2014 Aug 07;8(8):e3053
pubmed: 25101665
Lancet. 2018 Sep 15;392(10151):951-970
pubmed: 30126638
PLoS One. 2018 Sep 7;13(9):e0203407
pubmed: 30192805
BMC Public Health. 2013 Apr 24;13:382
pubmed: 23617595
Trends Ecol Evol. 2019 Jul;34(7):655-668
pubmed: 31078330