COSMOS next generation - A public knowledge base leveraging chemical and biological data to support the regulatory assessment of chemicals.
AOP, Adverse Outcome Pathway
Analogue selection
CERES, Chemical Evaluation and Risk Estimation System
CFSAN, Center for Food Safety and Applied Nutrition
CMS-ID, COSMOS Identification Number
COSMOS DB, COSMOS Database
COSMOS MINIS, Minimum Inclusion Criteria of Studies in COSMOS DB
COSMOS NG, COSMOS Next Generation
CRADA, Cooperative Research and Development Agreement
CosIng, Cosmetic Ingredient Database
DART, Developmental & Reproductive Toxicity
DB, Database
DST, Dempster Shafer Theory
Database
ECHA, European Chemicals Agency
EFSA, European Food Safety Authority
Guided workflow
HESS, Hazard Evaluation Support System
HNEL, Highest No Effect Level
HTS, High throughput screening
ILSI, International Life Sciences Institute
IUCLID, International Uniform Chemical Information Database
Knowledge hub
LEL, Lowest Effect Level
LOAEL, Lowest Observed Adverse Effect Level
LogP, Logarithm of the octanol:water partition coefficient
NAM, New Approach Methodology
NGRA, Next Generation Risk-Assessment
NITE, National Institute of Technology and Evaluation (Japan)
NOAEL, No Observed Adverse Effect Level
NTP, National Toxicology Program
OECD, Organisation for Economic Co-operation and Development
OpenFoodTox, EFSA’s OpenFoodTox database
PAFA, Priority-based Assessment of Food Additive database
PK/TK, Pharmacokinetics/Toxicokinetics
Public database
QA, Quality Assurance
QC, Quality Control
REACH, Registration, Evaluation, Authorisation and Restriction of Chemicals
SCC, Science Committee on Cosmetics (EU)
SCCNFP, Scientific Committee of Cosmetic Products and Non-food Products intended for Consumers (EU)
SCCP, Scientific Committee on Consumer Products (EU)
SCCS, Scientific Committee on Consumer Safety (EU)
Study reliability
TTC, Threshold of Toxicological Concern
ToxRefDB, Toxicity Reference Database
Toxicity
US EPA, United States Environmental Protection Agency
US FDA, United States Food and Drug Administration
Journal
Computational toxicology (Amsterdam, Netherlands)
ISSN: 2468-1113
Titre abrégé: Comput Toxicol
Pays: Netherlands
ID NLM: 101708081
Informations de publication
Date de publication:
Aug 2021
Aug 2021
Historique:
received:
13
04
2021
revised:
19
05
2021
accepted:
27
05
2021
entrez:
18
8
2021
pubmed:
19
8
2021
medline:
19
8
2021
Statut:
ppublish
Résumé
The COSMOS Database (DB) was originally established to provide reliable data for cosmetics-related chemicals within the COSMOS Project funded as part of the SEURAT-1 Research Initiative. The database has subsequently been maintained and developed further into COSMOS Next Generation (NG), a combination of database and
Identifiants
pubmed: 34405124
doi: 10.1016/j.comtox.2021.100175
pii: S2468-1113(21)00023-2
pmc: PMC8351204
doi:
Types de publication
Journal Article
Langues
eng
Pagination
100175Informations de copyright
© 2021 The Author(s).
Déclaration de conflit d'intérêts
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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