Completion of annual diabetes care processes and mortality: A cohort study using the National Diabetes Audit for England and Wales.


Journal

Diabetes, obesity & metabolism
ISSN: 1463-1326
Titre abrégé: Diabetes Obes Metab
Pays: England
ID NLM: 100883645

Informations de publication

Date de publication:
12 2021
Historique:
revised: 05 08 2021
received: 21 06 2021
accepted: 14 08 2021
pubmed: 19 8 2021
medline: 15 12 2021
entrez: 18 8 2021
Statut: ppublish

Résumé

To conduct an analysis to assess whether the completion of recommended diabetes care processes (glycated haemoglobin [HbA1c], creatinine, cholesterol, blood pressure, body mass index [BMI], smoking habit, urinary albumin, retinal and foot examinations) at least annually is associated with mortality. A cohort from the National Diabetes Audit of England and Wales comprising 179 105 people with type 1 and 1 397 790 people with type 2 diabetes, aged 17 to 99 years on January 1, 2009, diagnosed before January 1, 2009 and alive on April 1, 2013 was followed to December 31, 2019. Cox proportional hazards models adjusting for demographic characteristics, smoking, HbA1c, blood pressure, serum cholesterol, BMI, duration of diagnosis, estimated glomerular filtration rate, prior myocardial infarction, stroke, heart failure, respiratory disease and cancer, were used to investigate whether care processes recorded January 1, 2009 to March 31, 2010 were associated with subsequent mortality. Over a mean follow-up of 7.5 and 7.0 years there were 26 915 and 388 093 deaths in people with type 1 and type 2 diabetes, respectively. Completion of five or fewer, compared to eight, care processes (retinal screening not included as data were not reliable) had a mortality hazard ratio (HR) of 1.37 (95% confidence interval [CI] 1.28-1.46) in people with type 1 and 1.32 (95% CI 1.30-1.35) in people with type 2 diabetes. The HR was higher for respiratory disease deaths and lower in South Asian ethnic groups. People with diabetes who have fewer routine care processes have higher mortality. Further research is required into whether different approaches to care might improve outcomes for this high-risk group.

Identifiants

pubmed: 34405512
doi: 10.1111/dom.14528
doi:

Substances chimiques

Glycated Hemoglobin A 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2728-2740

Subventions

Organisme : British Heart Foundation
ID : RE/18/6/34217
Pays : United Kingdom

Informations de copyright

© 2021 The Authors. Diabetes, Obesity and Metabolism published by John Wiley & Sons Ltd.

Références

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Auteurs

Naomi Holman (N)

Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.

Peter Knighton (P)

Analytical Services - Population Health, Clinical Audit and Specialist Care, NHS Digital, Leeds, UK.

Jackie OʼKeefe (J)

Analytical Services - Population Health, Clinical Audit and Specialist Care, NHS Digital, Leeds, UK.

Sarah H Wild (SH)

College of Medicine and Veterinary Medicine, Usher Institute, University of Edinburgh, Edinburgh, UK.

Sarah Brewster (S)

West Hampshire Community Diabetes Service, Southern Health NHS Foundation Trust, Lyndhurst, UK.

Hermione Price (H)

West Hampshire Community Diabetes Service, Southern Health NHS Foundation Trust, Lyndhurst, UK.

Kiran Patel (K)

University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.
Warwick Medical School, University of Warwick, Warwick, UK.
Coventry University, Coventry, UK.

Wasim Hanif (W)

University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.

Vinod Patel (V)

Warwick Medical School, University of Warwick, Warwick, UK.
Diabetes and Endocrinology Centre, George Eliot Hospital NHS Trust, Nuneaton, UK.
West Midlands Clinical Networks and Clinical Senate, NHS England and NHS Improvement - Midlands, Birmingham, UK.

Edward W Gregg (EW)

School of Public Health, Imperial College, London, UK.

Richard I G Holt (RIG)

Human Development and Health, Faculty of Medicine, University of Southampton and Southampton National Institute for Health Research Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK.

Roger Gadsby (R)

Warwick Medical School, University of Warwick, Warwick, UK.

Kamlesh Khunti (K)

Diabetes Research Centre, University of Leicester, Leicester, UK.

Jonathan Valabhji (J)

NHS England and NHS Improvement, London, UK.
Department of Diabetes and Endocrinology, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK.
Division of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.

Bob Young (B)

Diabetes UK, London, UK.

Naveed Sattar (N)

Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.

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