Genome-wide interaction study reveals epistatic interactions for beef lipid-related traits in Nellore cattle.
Bos indicus
GWIS
epistasis
fatty acids
meat
Journal
Animal genetics
ISSN: 1365-2052
Titre abrégé: Anim Genet
Pays: England
ID NLM: 8605704
Informations de publication
Date de publication:
Feb 2022
Feb 2022
Historique:
accepted:
02
07
2021
pubmed:
19
8
2021
medline:
21
1
2022
entrez:
18
8
2021
Statut:
ppublish
Résumé
Gene-gene interactions cause hidden genetic variation in natural populations and could be responsible for the lack of replication that is typically observed in complex traits studies. This study aimed to identify gene-gene interactions using the empirical Hilbert-Schmidt Independence Criterion method to test for epistasis in beef fatty acid profile traits of Nellore cattle. The dataset contained records from 963 bulls, genotyped using a 777 962k SNP chip. Meat samples of Longissimus muscle, were taken to measure fatty acid composition, which was quantified by gas chromatography. We chose to work with the sums of saturated (SFA), monounsaturated (MUFA), polyunsaturated (PUFA), omega-3 (OM3), omega-6 (OM6), SFA:PUFA and OM3:OM6 fatty acid ratios. The SNPs in the interactions where
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
35-48Informations de copyright
© 2021 Stichting International Foundation for Animal Genetics.
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