A Comprehensive Understanding of Choroidal Metastasis from Lung Cancer.
cancer therapeutics
intraocular tumor
local therapy
systemic therapy
Journal
OncoTargets and therapy
ISSN: 1178-6930
Titre abrégé: Onco Targets Ther
Pays: New Zealand
ID NLM: 101514322
Informations de publication
Date de publication:
2021
2021
Historique:
received:
13
04
2021
accepted:
27
07
2021
entrez:
19
8
2021
pubmed:
20
8
2021
medline:
20
8
2021
Statut:
epublish
Résumé
The incidence of lung cancer with intraocular metastasis is low, of which choroidal metastasis is the most painful metastatic lesion. The clinical symptoms resulting from choroidal metastasis from lung cancer easily detected although they are rarely identified prior to the diagnosis of the primary malignancy. The quality of life of patients is inevitably impaired. Some lung cancer patients complain of ocular symptoms as the first manifestation of lung cancer. Early diagnosis and treatment can significantly overcome or delay the visual impairment and improve prognosis. The main therapeutic modalities include systemic and local treatments, while observation is also a treatment option. Currently, the feasibility and effectiveness of various treatment options are controversial worldwide. Herein, we summarize the underlying mechanisms, epidemiology, clinical features, auxiliary examinations, diagnosis, and recent treatment options for intraocular metastases.
Identifiants
pubmed: 34408441
doi: 10.2147/OTT.S315532
pii: 315532
pmc: PMC8367201
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
4451-4465Informations de copyright
© 2021 Qu et al.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest in this work.
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