Aerobic Exercise in the Management of Metabolic Dysfunction Associated Fatty Liver Disease.
aerobic exercise
metabolic dysfunction-associated fatty liver disease
physical activity
Journal
Diabetes, metabolic syndrome and obesity : targets and therapy
ISSN: 1178-7007
Titre abrégé: Diabetes Metab Syndr Obes
Pays: New Zealand
ID NLM: 101515585
Informations de publication
Date de publication:
2021
2021
Historique:
received:
25
05
2021
accepted:
29
07
2021
entrez:
19
8
2021
pubmed:
20
8
2021
medline:
20
8
2021
Statut:
epublish
Résumé
Sedentarism is the pandemic of modern times. It is associated with several medical conditions including obesity, type 2 diabetes mellitus, cardiovascular diseases and also liver disease, particularly metabolic dysfunction associated fatty liver disease (MAFLD). In an era when MAFLD is the most prevalent chronic liver disease worldwide, whilst no pharmacological therapy has been approved for it, exercise has proved to be effective in improving liver steatosis. Interestingly, exercise decreases liver fat even in the absence of weight loss. The challenge for the clinician is to motivate the obese patient with MAFLD, and associated co-morbidities, who has crystallized a sedentary behavior, at times when every need is at the distance of a click on the Internet, and the entire world can be visited behind a screen. In this review, the aggregate evidence on the mechanisms and effects of exercise in the management of MAFLD is summarized, with simple recommendations for everyday clinical practice.
Identifiants
pubmed: 34408459
doi: 10.2147/DMSO.S304357
pii: 304357
pmc: PMC8364841
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
3627-3645Informations de copyright
© 2021 Machado.
Déclaration de conflit d'intérêts
The author reports no conflicts of interest in this work.
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