Eosinophilic esophagitis: an interdisciplinary clinical problem.
allergy
atopy
endoscopy
eosinophilic esophagitis
glucocorticosteroids
Journal
Postepy dermatologii i alergologii
ISSN: 1642-395X
Titre abrégé: Postepy Dermatol Alergol
Pays: Poland
ID NLM: 101168357
Informations de publication
Date de publication:
Feb 2021
Feb 2021
Historique:
received:
10
06
2019
accepted:
29
06
2019
entrez:
19
8
2021
pubmed:
20
8
2021
medline:
20
8
2021
Statut:
ppublish
Résumé
Eosinophilic esophagitis is a newly described entity of increasing incidence. Previously thought to be a variation of gastroesophageal reflux disease, now it becomes well known among gastroenterologists, allergologists, paediatricians and pathologists. Aetiology of the disease is strongly correlated with atopic and allergic disorders but exact pathogenesis and cellular mechanisms of inflammatory process in the esophagus are still unknown. Diagnostic criteria have been described but diagnostic tools are still in the research and improvement phase. Clinical manifestation varies considerably between age groups, which causes a delay in the course of diagnosis due to improperly recognized symptoms. Since eosinophilic esophagitis is a chronic disease without a tendency to be self-limiting, delayed diagnosis may lead to complications associated with oesophageal tissue remodelling. Some forms of treatment are approved and of great therapeutical value, nevertheless clinical trials of new medications provide new possibilities. Therefore, many questions regarding eosinophilic esophagitis arise and are still unanswered.
Identifiants
pubmed: 34408564
doi: 10.5114/ada.2019.87237
pii: 37431
pmc: PMC8362782
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
36-42Informations de copyright
Copyright © 2021 Termedia.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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