Similar patterns of [
Children
Cognition
Complaints
Fatigue
SARS-CoV-2
Journal
European journal of nuclear medicine and molecular imaging
ISSN: 1619-7089
Titre abrégé: Eur J Nucl Med Mol Imaging
Pays: Germany
ID NLM: 101140988
Informations de publication
Date de publication:
02 2022
02 2022
Historique:
received:
15
07
2021
accepted:
06
08
2021
pubmed:
21
8
2021
medline:
4
2
2022
entrez:
20
8
2021
Statut:
ppublish
Résumé
Several weeks after COVID-19 infection, some children report the persistence or recurrence of functional complaints. This clinical presentation has been referred as "long COVID" in the adult population, and an [ Review of clinical examination and whole-brain voxel-based analysis of [ Despite lower initial severity at the acute stage of the infection, paediatric patients demonstrated on average 5 months later a similar brain hypometabolic pattern as that found in adult long COVID patients, involving bilateral medial temporal lobes, brainstem and cerebellum (p-voxel < 0.001, p-cluster < 0.05 FWE-corrected), and also the right olfactory gyrus after small volume correction (p-voxel = 0.010 FWE-corrected), with partial PET recovery in two children at follow-up. These results provide arguments in favour of possible long COVID in children, with a similar functional brain involvement to those found in adults, regardless of age and initial severity.
Identifiants
pubmed: 34414470
doi: 10.1007/s00259-021-05528-4
pii: 10.1007/s00259-021-05528-4
pmc: PMC8376118
doi:
Substances chimiques
Fluorodeoxyglucose F18
0Z5B2CJX4D
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
913-920Subventions
Organisme : aphm
ID : PHRC 07 09
Informations de copyright
© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
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