Chronic, Multi-Site Recordings Supported by Two Low-Cost, Stationary Probe Designs Optimized to Capture Either Single Unit or Local Field Potential Activity in Behaving Rats.
electrophysiology
field potentials
fixed array
multi-site recordings
rodent models
single unit
Journal
Frontiers in psychiatry
ISSN: 1664-0640
Titre abrégé: Front Psychiatry
Pays: Switzerland
ID NLM: 101545006
Informations de publication
Date de publication:
2021
2021
Historique:
received:
08
03
2021
accepted:
21
06
2021
entrez:
23
8
2021
pubmed:
24
8
2021
medline:
24
8
2021
Statut:
epublish
Résumé
Rodent models of cognitive behavior have greatly contributed to our understanding of human neuropsychiatric disorders. However, to elucidate the neurobiological underpinnings of such disorders or impairments, animal models are more useful when paired with methods for measuring brain function in awake, behaving animals. Standard tools used for systems-neuroscience level investigations are not optimized for large-scale and high-throughput behavioral battery testing due to various factors including cost, time, poor longevity, and selective targeting limited to measuring only a few brain regions at a time. Here we describe two different "user-friendly" methods for building extracellular electrophysiological probes that can be used to measure either single units or local field potentials in rats performing cognitive tasks. Both probe designs leverage several readily available, yet affordable, commercial products to facilitate ease of production and offer maximum flexibility in terms of brain-target locations that can be scalable (32-64 channels) based on experimental needs. Our approach allows neural activity to be recorded simultaneously with behavior and compared between micro (single unit) and more macro (local field potentials) levels of brain activity in order to gain a better understanding of how local brain regions and their connected networks support cognitive functions in rats. We believe our novel probe designs make collecting electrophysiology data easier and will begin to fill the gap in knowledge between basic and clinical research.
Identifiants
pubmed: 34421671
doi: 10.3389/fpsyt.2021.678103
pmc: PMC8374626
doi:
Types de publication
Journal Article
Langues
eng
Pagination
678103Informations de copyright
Copyright © 2021 Francoeur, Tang, Fakhraei, Wu, Hulyalkar, Cramer, Buscher and Ramanathan.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
J Neurophysiol. 2001 Oct;86(4):2029-40
pubmed: 11600659
Sci Adv. 2020 Mar 20;6(12):eaay2789
pubmed: 32219158
J Neurosci Methods. 2004 Sep 30;138(1-2):97-105
pubmed: 15325117
J Cogn Neurosci. 1995 Winter;7(1):1-24
pubmed: 23961750
Elife. 2020 Oct 22;9:
pubmed: 33089778
Curr Top Behav Neurosci. 2016;28:93-120
pubmed: 27418069
Neuron. 2015 Apr 8;86(1):92-105
pubmed: 25856489
Nat Protoc. 2013 Oct;8(10):1985-2005
pubmed: 24051960
Neural Comput. 2004 Aug;16(8):1661-87
pubmed: 15228749
Transl Psychiatry. 2020 Aug 13;10(1):285
pubmed: 32792526
Front Syst Neurosci. 2014 Feb 10;8:6
pubmed: 24574979
J Neurosci. 2017 Feb 22;37(8):2010-2021
pubmed: 28115481
J Neurophysiol. 2018 Oct 1;120(4):2083-2090
pubmed: 30020844
Science. 2018 Jul 13;361(6398):178-181
pubmed: 30002252
J Neurophysiol. 2014 Oct 1;112(7):1748-62
pubmed: 24966298
Mol Autism. 2019 Dec 2;10:42
pubmed: 31827744
IEEE Trans Biomed Eng. 2004 Jun;51(6):896-904
pubmed: 15188856
Nat Protoc. 2008;3(5):759-67
pubmed: 18451784
Annu Int Conf IEEE Eng Med Biol Soc. 2008;2008:5794-7
pubmed: 19164034
J Neurosci Methods. 2011 Oct 15;201(2):368-76
pubmed: 21889539
Science. 2004 Jun 25;304(5679):1926-9
pubmed: 15218136
IEEE Trans Neural Syst Rehabil Eng. 2003 Jun;11(2):151-5
pubmed: 12899260
Front Syst Neurosci. 2013 May 13;7:8
pubmed: 23717267
Cereb Cortex. 2006 Jan;16(1):106-14
pubmed: 15829733
Prog Neurobiol. 2013 Sep;108:44-79
pubmed: 23856628
Neuron. 2010 Nov 4;68(3):362-85
pubmed: 21040841
Heliyon. 2020 Sep 14;6(9):e04867
pubmed: 32984592
J Neurosci Methods. 2011 Feb 15;195(2):117-27
pubmed: 20868709
Nature. 2017 Nov 8;551(7679):232-236
pubmed: 29120427
J Neurosci Methods. 2020 Aug 1;342:108761
pubmed: 32479970
Neuron. 2011 Feb 24;69(4):680-94
pubmed: 21338879
iScience. 2020 Aug 21;23(8):101387
pubmed: 32745989
J Neurosci Methods. 1999 Oct 15;92(1-2):87-90
pubmed: 10595706
PLoS One. 2016 Feb 05;11(2):e0149019
pubmed: 26848579
Neurotox Res. 2008 Oct;14(2-3):249-62
pubmed: 19073430
Nat Rev Neurosci. 2013 Nov;14(11):770-85
pubmed: 24135696
Biomaterials. 2007 Sep;28(25):3594-607
pubmed: 17517431
Neurosci Biobehav Rev. 2004 Nov;28(7):771-84
pubmed: 15555683
eNeuro. 2017 Aug 7;4(4):
pubmed: 28791332
Electroencephalogr Clin Neurophysiol. 1997 Mar;102(3):228-39
pubmed: 9129578
J Neural Eng. 2006 Mar;3(1):59-70
pubmed: 16510943
Nat Rev Neurosci. 2012 May 18;13(6):407-20
pubmed: 22595786
Nat Med. 2018 Aug;24(8):1257-1267
pubmed: 29915259
Brain Res Bull. 2015 Oct;119(Pt B):106-17
pubmed: 25931392
Nat Neurosci. 2016 Aug 26;19(9):1165-74
pubmed: 27571195
Biomaterials. 2015 Jan;37:25-39
pubmed: 25453935
J Neural Eng. 2020 Apr 29;17(2):026037
pubmed: 32209743
Behav Pharmacol. 2011 Aug;22(4):300-11
pubmed: 21694584
J Neural Eng. 2017 Aug;14(4):045003
pubmed: 28169219
J Neurotrauma. 2017 Oct 1;34(19):2790-2800
pubmed: 28376700
Front Neuroeng. 2014 Feb 04;7:2
pubmed: 24550823
Curr Top Behav Neurosci. 2016;28:231-62
pubmed: 26873017
Prog Brain Res. 1990;85:31-62
pubmed: 2094901
Micromachines (Basel). 2016 Oct 02;7(10):
pubmed: 30404352
J Neurosci Methods. 2017 Dec 1;292:53-60
pubmed: 28754432
Neuron. 2006 Aug 17;51(4):495-507
pubmed: 16908414
Pharmacol Biochem Behav. 2014 Mar;118:1-9
pubmed: 24388843
Front Neural Circuits. 2016 Dec 15;10:101
pubmed: 28018180
J Neurosci. 2012 Nov 7;32(45):16051-63
pubmed: 23136441
J Neural Eng. 2012 Oct;9(5):056015
pubmed: 23010756
Nat Rev Neurosci. 2019 Jun;20(6):330-345
pubmed: 30833706
Genes Brain Behav. 2021 Jan;20(1):e12650
pubmed: 32141694
J Vis Exp. 2012 Mar 04;(61):e3568
pubmed: 22415550
J Neurotrauma. 2016 Oct 15;33(20):1892-1900
pubmed: 26756392
Adv Mater. 2015 Jul 22;27(28):4186-93
pubmed: 26074252
Neuron. 2020 Oct 28;108(2):302-321
pubmed: 33120025
J Neurosci. 2010 Jun 2;30(22):7705-13
pubmed: 20519545
Front Neurosci. 2015 Jan 06;8:423
pubmed: 25610364
Behav Neurosci. 2011 Jun;125(3):327-43
pubmed: 21639603
Psychopharmacology (Berl). 2015 Nov;232(21-22):4005-16
pubmed: 26264904
Front Neurosci. 2019 Feb 21;13:128
pubmed: 30846926
eNeuro. 2019 Jan 7;5(6):
pubmed: 30627656
Hum Mol Genet. 2017 Oct 15;26(20):3995-4010
pubmed: 29016856
J Neurosci Methods. 2005 Oct 15;148(1):1-18
pubmed: 16198003
Neuroscience. 2005;131(1):1-11
pubmed: 15680687
J Neurophysiol. 2018 Oct 1;120(4):1859-1871
pubmed: 29995603
J Neural Eng. 2015 Aug;12(4):046009
pubmed: 26035638
J Neurophysiol. 2005 Jan;93(1):570-9
pubmed: 15229215
J Neurosci Methods. 2005 Mar 30;142(2):169-76
pubmed: 15698656
Crit Rev Biomed Eng. 2013;41(6):435-56
pubmed: 24940658
Nat Neurosci. 2008 Jul;11(7):823-33
pubmed: 18516033
Neuron. 1997 Apr;18(4):529-37
pubmed: 9136763
J Neurosci Methods. 2007 Feb 15;160(1):122-7
pubmed: 17067683
Mol Neurobiol. 2019 Sep;56(9):6276-6292
pubmed: 30746640
J Neural Eng. 2006 Dec;3(4):316-26
pubmed: 17124336
eNeuro. 2021 Feb 26;8(1):
pubmed: 33509949
Genes Brain Behav. 2021 Jan;20(1):e12723
pubmed: 33347690
J Physiol Paris. 2016 Nov;110(4 Pt A):327-335
pubmed: 28263793
Nat Neurosci. 2018 Jul;21(7):903-919
pubmed: 29942039
Cell. 2018 Mar 22;173(1):166-180.e14
pubmed: 29502969
Clin Psychol Rev. 2006 Aug;26(4):379-95
pubmed: 16504359
J Neurosci. 2012 Feb 8;32(6):2129-41
pubmed: 22323725
Biomaterials. 2013 Nov;34(33):8061-74
pubmed: 23891081
Biomaterials. 2015;53:753-62
pubmed: 25890770
J Neural Eng. 2020 May 19;17(2):026044
pubmed: 32074511
Front Syst Neurosci. 2017 May 11;11:27
pubmed: 28553206
Nat Commun. 2014 Jun 04;5:3926
pubmed: 24894805
Elife. 2019 Aug 14;8:
pubmed: 31411559
eNeuro. 2018 Oct 25;5(5):
pubmed: 30406193
Trends Neurosci. 2017 Apr;40(4):208-218
pubmed: 28314445