Time to Evacuation and Functional Outcome After Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation.


Journal

Stroke
ISSN: 1524-4628
Titre abrégé: Stroke
Pays: United States
ID NLM: 0235266

Informations de publication

Date de publication:
08 2021
Historique:
entrez: 23 8 2021
pubmed: 24 8 2021
medline: 6 1 2022
Statut: ppublish

Résumé

We present a retrospective analysis of patients who underwent minimally invasive endoscopic intracerebral hemorrhage (ICH) evacuation to identify variables that were associated with long-term outcome. Minimally invasive endoscopic ICH evacuation was performed on patients with supratentorial ICH who fit prespecified clinical inclusion and exclusion criteria. Demographic, clinical, and radiographic factors previously demonstrated to impact functional outcome in ICH were included in a univariate analysis to identify factors associated with favorable outcome (modified Rankin Scale score, 0-3) at 6 months. Factors associated with a favorable outcome in the univariate analysis ( Ninety patients underwent MIS endoscopic ICH evacuation within 72 hours of ictus. In a multivariate analysis, factors associated with good long-term functional outcome included time to evacuation (per hour; OR, 0.95 [95% CI, 0.92-0.98], Young age, lack of intraventricular hemorrhage, lobar location, and time to evacuation were independently associated with good long-term functional outcome in patients undergoing minimally invasive endoscopic ICH evacuation. The OR for time to evacuation suggests that for each additional hour, there was a 5% reduction in the odds of achieving a favorable outcome.

Sections du résumé

BACKGROUND AND PURPOSE
We present a retrospective analysis of patients who underwent minimally invasive endoscopic intracerebral hemorrhage (ICH) evacuation to identify variables that were associated with long-term outcome.
METHODS
Minimally invasive endoscopic ICH evacuation was performed on patients with supratentorial ICH who fit prespecified clinical inclusion and exclusion criteria. Demographic, clinical, and radiographic factors previously demonstrated to impact functional outcome in ICH were included in a univariate analysis to identify factors associated with favorable outcome (modified Rankin Scale score, 0-3) at 6 months. Factors associated with a favorable outcome in the univariate analysis (
RESULTS
Ninety patients underwent MIS endoscopic ICH evacuation within 72 hours of ictus. In a multivariate analysis, factors associated with good long-term functional outcome included time to evacuation (per hour; OR, 0.95 [95% CI, 0.92-0.98],
CONCLUSIONS
Young age, lack of intraventricular hemorrhage, lobar location, and time to evacuation were independently associated with good long-term functional outcome in patients undergoing minimally invasive endoscopic ICH evacuation. The OR for time to evacuation suggests that for each additional hour, there was a 5% reduction in the odds of achieving a favorable outcome.

Identifiants

pubmed: 34424739
doi: 10.1161/STROKEAHA.121.034392
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e536-e539

Auteurs

Christopher P Kellner (CP)

Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, NY.

Rui Song (R)

Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, NY.

Muhammad Ali (M)

Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, NY.

Dominic A Nistal (DA)

Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, NY.

Milan Samarage (M)

Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, NY.

Neha S Dangayach (NS)

Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, NY.

John Liang (J)

Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, NY.

Ian McNeill (I)

Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, NY.

Xiangnan Zhang (X)

Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, NY.

Joshua B Bederson (JB)

Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, NY.

J Mocco (J)

Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, NY.

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Classifications MeSH