Antifibrotic effect of lung-resident progenitor cells with high aldehyde dehydrogenase activity.
Aldehyde dehydrogenase
Bleomycin
Cell therapy
Profibrotic cytokines
Pulmonary fibrosis
Stem cells
Journal
Stem cell research & therapy
ISSN: 1757-6512
Titre abrégé: Stem Cell Res Ther
Pays: England
ID NLM: 101527581
Informations de publication
Date de publication:
23 08 2021
23 08 2021
Historique:
received:
09
05
2021
accepted:
08
08
2021
entrez:
24
8
2021
pubmed:
25
8
2021
medline:
30
10
2021
Statut:
epublish
Résumé
Aldehyde dehydrogenase (ALDH) is highly expressed in stem/progenitor cells in various tissues, and cell populations with high ALDH activity (ALDH The characteristics of lung-resident/nonhematopoietic (CD45 Lung CD45 Our results strongly suggest that the lung expression of ALDH and lung-resident CD45
Sections du résumé
BACKGROUND
Aldehyde dehydrogenase (ALDH) is highly expressed in stem/progenitor cells in various tissues, and cell populations with high ALDH activity (ALDH
METHODS
The characteristics of lung-resident/nonhematopoietic (CD45
RESULTS
Lung CD45
CONCLUSIONS
Our results strongly suggest that the lung expression of ALDH and lung-resident CD45
Identifiants
pubmed: 34425896
doi: 10.1186/s13287-021-02549-6
pii: 10.1186/s13287-021-02549-6
pmc: PMC8381511
doi:
Substances chimiques
Bleomycin
11056-06-7
Aldehyde Dehydrogenase
EC 1.2.1.3
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
471Informations de copyright
© 2021. The Author(s).
Références
Stem Cells. 2005 Sep;23(8):1073-81
pubmed: 15987674
Am J Respir Cell Mol Biol. 2005 Aug;33(2):145-52
pubmed: 15891110
Biochem Biophys Res Commun. 2017 Sep 23;491(3):721-726
pubmed: 28743499
Stem Cells Int. 2010 Mar 08;2010:868076
pubmed: 21048855
Am J Respir Cell Mol Biol. 2007 Aug;37(2):152-9
pubmed: 17395889
Lung Cancer. 2008 Mar;59(3):340-9
pubmed: 17920722
Cytotherapy. 2007;9(3):259-74
pubmed: 17464758
World J Stem Cells. 2017 Oct 26;9(10):179-186
pubmed: 29104736
Free Radic Biol Med. 2014 Mar;68:80-6
pubmed: 24316006
Biomed Res Int. 2013;2013:503047
pubmed: 23484127
Am J Respir Crit Care Med. 2013 Oct 15;188(8):976-84
pubmed: 24010731
Cytotherapy. 2008;10(2):140-51
pubmed: 18368593
Am J Respir Crit Care Med. 2019 Oct 15;200(8):1032-1044
pubmed: 31106564
Stem Cells Dev. 2010 Apr;19(4):523-36
pubmed: 19848595
Am J Pathol. 2014 May;184(5):1369-83
pubmed: 24631025
Stem Cells. 2004;22(7):1142-51
pubmed: 15579635
Am J Physiol Lung Cell Mol Physiol. 2003 Jul;285(1):L97-104
pubmed: 12626330
Blood. 2007 Jul 1;110(1):151-60
pubmed: 17379743
World J Stem Cells. 2014 Nov 26;6(5):552-70
pubmed: 25426252
J Transl Med. 2010 Mar 09;8:24
pubmed: 20214792
Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5099-104
pubmed: 25840590
Stem Cells. 2011 Apr;29(4):725-35
pubmed: 21312316
Stem Cell Rev Rep. 2011 Jun;7(2):292-306
pubmed: 21103958
J Pathol. 2010 Dec;222(4):335-44
pubmed: 20848663
Stem Cells Transl Med. 2012 Oct;1(10):719-24
pubmed: 23197663
Exp Lung Res. 2012 Mar;38(2):82-9
pubmed: 22250783
Respirology. 2016 Nov;21(8):1366-1375
pubmed: 27688156
Stem Cells Dev. 2009 Jan-Feb;18(1):17-25
pubmed: 18573038
Cell Stem Cell. 2007 Nov;1(5):555-67
pubmed: 18371393
Expert Opin Biol Ther. 2008 May;8(5):569-81
pubmed: 18407762
Am J Respir Crit Care Med. 2006 Dec 15;174(12):1352-60
pubmed: 17023731
Stem Cell Reports. 2014 Jun 03;2(6):910-24
pubmed: 24936475
Lab Invest. 2013 Nov;93(11):1219-31
pubmed: 24042439
Stem Cells. 2016 Apr;34(4):873-87
pubmed: 26676482
Blood. 2009 May 21;113(21):5340-51
pubmed: 19324906
Free Radic Biol Med. 2012 Feb 15;52(4):735-46
pubmed: 22206977
N Engl J Med. 2020 Sep 3;383(10):958-968
pubmed: 32877584
Nutrients. 2014 Mar 21;6(3):1209-22
pubmed: 24662164
Am J Physiol Lung Cell Mol Physiol. 2002 Nov;283(5):L1023-32
pubmed: 12376355
Stem Cells. 2011 Apr;29(4):570-5
pubmed: 21308868