Lung ultrasound may support internal medicine physicians in predicting the diagnosis, bacterial etiology and favorable outcome of community-acquired pneumonia.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
23 08 2021
23 08 2021
Historique:
received:
16
05
2021
accepted:
09
08
2021
entrez:
24
8
2021
pubmed:
25
8
2021
medline:
5
11
2021
Statut:
epublish
Résumé
To assess the usefulness of lung ultrasound (LUS) for identifying community-acquired pneumonia (CAP) among adult patients with suspected lower respiratory tract infection (LRTI) and for discriminating between CAP with different cultural statuses, etiologies, and outcomes. LUS was performed at internal medicine ward admission. The performance of chest X-ray (CXR) and LUS in diagnosing CAP in 410 patients with suspected LRTI was determined. All possible positive results for pneumonia on LUS were condensed into pattern 1 (consolidation + / - alveolar-interstitial syndrome) and pattern 2 (alveolar-interstitial syndrome). The performance of LUS in predicting culture-positive status, bacterial etiology, and adverse outcomes of CAP was assessed in 315 patients. The area under the receiver operating characteristic curve for diagnosing CAP by LUS was significantly higher than for diagnosis CAP by CXR (0.93 and 0.71, respectively; p < 0.001). Pattern 1 predicted CAP with bacterial and mixed bacterial and viral etiologies with positive predictive values of 99% (95% CI, 94-100%) and 97% (95% CI, 81-99%), respectively. Pattern 2 ruled out mortality with a negative predictive value of 95% (95% CI, 86-98%), respectively. In this study, LUS was useful in predicting a diagnosis of CAP, the bacterial etiology of CAP, and favorable outcome in patients with CAP.
Identifiants
pubmed: 34426615
doi: 10.1038/s41598-021-96380-x
pii: 10.1038/s41598-021-96380-x
pmc: PMC8382746
doi:
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
17016Informations de copyright
© 2021. The Author(s).
Références
Expert Rev Respir Med. 2019 Jan;13(1):63-77
pubmed: 30518278
Sci Rep. 2019 Nov 29;9(1):17957
pubmed: 31784642
N Engl J Med. 2014 Oct 23;371(17):1619-28
pubmed: 25337751
PLoS One. 2015 Jun 24;10(6):e0130066
pubmed: 26107512
Lancet. 2011 Apr 9;377(9773):1264-75
pubmed: 21435708
Respiration. 2015;89(4):343-52
pubmed: 25791384
Crit Care. 2016 Oct 25;20(1):375
pubmed: 27852281
N Engl J Med. 2015 Jul 30;373(5):415-27
pubmed: 26172429
Intensive Care Med. 2017 Jan;43(1):48-58
pubmed: 27709265
Intensive Care Med. 2004 Feb;30(2):276-281
pubmed: 14722643
Chest. 2017 Feb;151(2):374-382
pubmed: 27818332
Diagn Microbiol Infect Dis. 2019 May;94(1):50-54
pubmed: 30578007
Clin Microbiol Infect. 2011 Nov;17 Suppl 6:E1-59
pubmed: 21951385
Curr Opin Pulm Med. 2014 May;20(3):215-24
pubmed: 24614242
Am J Respir Crit Care Med. 2019 Oct 1;200(7):e45-e67
pubmed: 31573350
Intensive Care Med. 2011 Sep;37(9):1488-93
pubmed: 21809107
Thorax. 2013 Nov;68(11):1000-6
pubmed: 23783373
Medicine (Baltimore). 2017 Jan;96(3):e5713
pubmed: 28099332
Pediatr Radiol. 2020 Oct;50(11):1560-1569
pubmed: 32821992
Respir Res. 2014 Apr 23;15:50
pubmed: 24758612
Eur Respir Rev. 2016 Jun;25(140):178-88
pubmed: 27246595
BMJ. 2017 Jul 10;358:j2471
pubmed: 28694251
Intensive Care Med. 2017 Mar;43(3):304-377
pubmed: 28101605
Lancet. 2003 Dec 13;362(9400):1991-2001
pubmed: 14683661
J Med Microbiol. 2014 Mar;63(Pt 3):441-452
pubmed: 24344207
Clin Infect Dis. 2018 May 2;66(10):1640-1641
pubmed: 29360954
Anesthesiology. 2004 Jan;100(1):9-15
pubmed: 14695718